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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">thealth</journal-id><journal-title-group><journal-title xml:lang="ru">Здравоохранение Таджикистана</journal-title><trans-title-group xml:lang="en"><trans-title>Health care of Tajikistan</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0514-2415</issn><publisher><publisher-name>Редакция журнала «Здравоохранение Таджикистана»</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">thealth-286</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group></article-categories><title-group><article-title>Состояние гемостаза у больных с сочетанной травмой таза</article-title><trans-title-group xml:lang="en"><trans-title>The status of hemostasis in patients with concomitant pelvic trauma</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сафаров</surname><given-names>А. Х.</given-names></name><name name-style="western" xml:lang="en"><surname>Safarov</surname><given-names>A. Kh.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кафедра травматологии и ортопедии</p></bio><bio xml:lang="en"><p>Traumatology and Orthopedics Department</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сироджов</surname><given-names>К. Х.</given-names></name><name name-style="western" xml:lang="en"><surname>Sirojov</surname><given-names>K. Kh.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кафедра травматологии и ортопедии</p></bio><bio xml:lang="en"><p>Traumatology and Orthopedics Department</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Косимов</surname><given-names>З. К.</given-names></name><name name-style="western" xml:lang="en"><surname>Kosimov</surname><given-names>Z. K.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кафедра анестезиологии и реаниматологии</p></bio><bio xml:lang="en"><p>Department of anesthesiology and resuscitation</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Хамидов</surname><given-names>Д. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Khamidov</surname><given-names>D. B.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Хамидов Джура Бутаевич – к.м.н.; доцент кафедры анестезиологи и реаниматологии</p><p>тел: +(992)985530062</p></bio><bio xml:lang="en"><p>Dzhura Butaevich Khamidov - Candidate of Medical Sciences; Assistant Professor of Anesthesiology and Resuscitation Department</p><p>tel: +(992)985530062</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ГОУ «ИПОвСЗРТ»</institution><country>Таджикистан</country></aff><aff xml:lang="en"><institution>SEI “Institute of Postgraduate Education in Spere of a Healthcare of the Republic of Tajikistan”</institution><country>Tajikistan</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2020</year></pub-date><pub-date pub-type="epub"><day>22</day><month>01</month><year>2022</year></pub-date><volume>0</volume><issue>4</issue><fpage>44</fpage><lpage>48</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Сафаров А.Х., Сироджов К.Х., Косимов З.К., Хамидов Д.Б., 2022</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="ru">Сафаров А.Х., Сироджов К.Х., Косимов З.К., Хамидов Д.Б.</copyright-holder><copyright-holder xml:lang="en">Safarov A.K., Sirojov K.K., Kosimov Z.K., Khamidov D.B.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.zdrav.tj/jour/article/view/286">https://www.zdrav.tj/jour/article/view/286</self-uri><abstract><sec><title>Цель исследования</title><p>Цель исследования. Изучить состояние гемостаза у больных с сочетанной травмой таза.</p><p>Материалы и методы исследования. У 93 больных с сочетанной травмой таза исследовано состояние гемостаза с помощью коагулологических тестов. Контрольную группу составили 20 человек.</p><p>Результаты исследования и их обсуждение. Выявлено повышение коагуляционных свойств крови на фоне угнетения показателей фибринолитической и антикоагулятной систем. Наряду с этим, отмечено повышение содержания продуктов распада фибриногена.</p></sec><sec><title>Заключение</title><p>Заключение. Таким образом, у больных с сочетанной травмой таза наблюдается повышение коагуляционного потенциала крови, угнетение активности её фибринолитической и антикоагулянтной систем. Также появление продуктов распада фибриногена свидетельствуют об изменениях гемостаза по типу подострой формы ДВС-синдрома.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Aim</title><p>Aim. To study the state of hemostasis in patients with concomitant trauma of the pelvis.</p></sec><sec><title>Materials and methods</title><p>Materials and methods. 93 patients with concomitant pelvic trauma the state of hemostasis were examined by coagulation tests. The control group included 20 patients.</p></sec><sec><title>Results and discussion</title><p>Results and discussion. An increase of blood coagulation properties was revealed on the background of inhibition of fibrinolytic and anticoagulative system indexes. At the same time, there was an increase in the content of fibrinogen decomposition products.</p></sec><sec><title>Conclusion</title><p>Conclusion. Thus, an increase of blood coagulation potential, suppression of the activity of its fibrinolytic and anticoagulant systems are observed in patients with combined pelvic trauma. Also, the appearance of products of fibrinogen decomposition proves the changes of hemostasis by the type of subacute form of DIC syndrome.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>сочетанная травма таза</kwd><kwd>гемостаз</kwd><kwd>ДВС-синдром</kwd></kwd-group><kwd-group xml:lang="en"><kwd>combined pelvic trauma</kwd><kwd>hemostasis</kwd><kwd>DIC syndrome</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Власов А.А. Системный коагуляционно-литический дистресс – синдром при травматической болезни / А.А. Власов, Г.А. Шевалаев // Травматология и ортопедия России. - 2014. №1(71). - С. 80-85.</mixed-citation><mixed-citation xml:lang="en">Vlasov A. A. Sistemnyy koagulyatsionno-liticheskiy distress – sindrom pri travmaticheskoy bolezni [Systemic Coagulation-Lytic Distress Syndrome in Traumatic Illness]. Travmatologiya i ortopediya Rossii - Traumatology and Orthopedics of Russia, 2014, No. 1 (71), pp. 80-85.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Рипп Е.Г. Значение экспресс-диагностики дисфункции системы гемостаза у больных с травмой и острой кровопотерей / Е.Г. Рипп, М.Н. Шписман // Общая реаниматология. – 2010. - №3. - С. 57-59.</mixed-citation><mixed-citation xml:lang="en">Ripp E. G. Znachenie ekspress–diagnostiki disfunktsii sistemy gemostaza u bolnykh s travmoy i ostroy krovopoterey [The value of rapid diagnostics of hemostasis system dysfunction in patients with trauma and acute blood loss]. Obshchaya reanimatologiya General resuscitation, 2010, Vol. 3, pp. 57-59.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Сабурова А.М. Показатели гемостаза и перекисного окисления липидов в крови больных с абдоминальной травмой / А.М. Сабурова, К.М. Курбонов, Ш.Д. Рахмонов, // Доклады академии наук Республики Таджикистан. 2012. - Т. 55, № 11. - С. 913-917.</mixed-citation><mixed-citation xml:lang="en">Saburova A. M. Pokazateli gemostaza i perekisnogo okisleniya lipidov v krovi bolnykh s abdominalnoy travmoy [Hemostasis and lipid peroxidation parameters in the blood of patients with abdominal trauma]. Doklady akademii nauk Respubliki Tadzhikistan - Reports of the Academy of Sciences of the Republic of Tajikistan, 2012, Vol. 55, No. 11, pp. 913- 917.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Сирозитдинов С.Д. Совершенствование методов диагностики и профилактики ранних осложнений травматической болезни при множественных переломах костей конечности / С.Д. Сирозитдинов, И.О. Панков // Кафедра травматологии и ортопедии. - 2016. - № 1 (17). - С. 36-39.</mixed-citation><mixed-citation xml:lang="en">Sirozitdinov S. D. Sovershenstvovanie metodov diagnostiki i profilaktiki rannikh oslozhneniy travmaticheskoy bolezni pri mnozhestvennykh perelomakh kostey konechnosti [Improvement of methods of diagnosis and prevention of early complications of traumatic disease in multiple fractures of limb bones]. Kafedra travmatologii i ortopedii - Department of Traumatology and Orthopedics, 2016, No. 1 (17), pp. 36-39.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Скипетров В.П. Коагуляционно-литическая система тканей и тромбогеморрагический синдром в хирургии. / В.П. Скипетров, А.П. Власов С.П. Голышенков // Саранск; Изд-во Мардовского гос. Университета. 2011. - 192 с.</mixed-citation><mixed-citation xml:lang="en">Skipetrov V. P. Koagulyatsionno–liticheskaya sistema tkaney i trombogemorragicheskiy sindrom v khirurgii [Coagulation and lytic system of tissues and thrombohemorrhagic syndrome in surgery]. Saransk, Izdatelstvo Mardovskogo gosudarstvennogo universiteta Publ., 2011. 192 p.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Шильков И.Л. Гемостазиологическая оценка степени тяжести состояния пациента с травмой таза / И.Л. Шильков, Н.Л. Кузнецова и др. // Политравма. - 2012. - №1. - С. 54-59.</mixed-citation><mixed-citation xml:lang="en">Shilkov I. L. Gemostaziologicheskaya otsenka stepeni tyazhesti sostoyaniya patsienta s travmoy taza [Hemostasis assessment of the severity of a patient with pelvic trauma]. Politravma - Polytrauma, 2012, No.1, pp. 54-59.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Brohi K. Acute coagulopathy of trauma: hypoperfusion induces systemic anticoagulation and hyperfibrinolysis. Journal of Trauma and Acute Care Surgery. 2008, Vol. 64, No. 5, pp. 1211-1217.</mixed-citation><mixed-citation xml:lang="en">Brohi K. Acute coagulopathy of trauma: hypoperfusion induces systemic anticoagulation and hyperfibrinolysis. Journal of Trauma and Acute Care Surgery. 2008, Vol. 64, No. 5, pp. 1211-1217.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Pavić R. Emergency treatment for clinically unstable patients with pelvic fracture and haemorrhage. Collegium Antropologicum, 2012, Vol. 36, No. 4, pp. 1445–52.</mixed-citation><mixed-citation xml:lang="en">Pavić R. Emergency treatment for clinically unstable patients with pelvic fracture and haemorrhage. Collegium Antropologicum, 2012, Vol. 36, No. 4, pp. 1445–52.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
