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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">thealth</journal-id><journal-title-group><journal-title xml:lang="ru">Здравоохранение Таджикистана</journal-title><trans-title-group xml:lang="en"><trans-title>Health care of Tajikistan</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0514-2415</issn><publisher><publisher-name>Редакция журнала «Здравоохранение Таджикистана»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.52888/0514-2515-2022-352-1-17-23</article-id><article-id custom-type="elpub" pub-id-type="custom">thealth-337</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group></article-categories><title-group><article-title>Роль вирусной инфекции в патологии слизистой оболочки полости рта у лиц с ортопедическими конструкциями</article-title><trans-title-group xml:lang="en"><trans-title>The role of viral infection in the pathology of oral mucosa in persons with prosthetic constructions</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Артыкова</surname><given-names>Н. К.</given-names></name><name name-style="western" xml:lang="en"><surname>Artykova</surname><given-names>N. K.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Артыкова Нигина Каримджоновна - соискатель кафедры ортопедической стоматологии</p><p>734000, г. Душанбе, ул. Бохтар 65/1, кв. 17</p><p>тел.: +(992)985806633</p></bio><bio xml:lang="en"><p>Nigina Karimdjonovna Artykova - candidate of sciences, chair of orthopedic stomatology, Department of Orthopedic Dentistry</p><p>734000, 65/1 Bokhtar str., bldg. 17</p><p>Tel: +(992)985806633</p></bio><email xlink:type="simple">nigina_artikova@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ГОУ ИПОСЗ РТ</institution><country>Таджикистан</country></aff><aff xml:lang="en"><institution>State Educational Institution of Postgraduate Professional Education and Dentistry of the Republic of Tajikistan</institution><country>Tajikistan</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2022</year></pub-date><pub-date pub-type="epub"><day>29</day><month>04</month><year>2022</year></pub-date><volume>0</volume><issue>1</issue><fpage>17</fpage><lpage>23</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Артыкова Н.К., 2022</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="ru">Артыкова Н.К.</copyright-holder><copyright-holder xml:lang="en">Artykova N.K.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.zdrav.tj/jour/article/view/337">https://www.zdrav.tj/jour/article/view/337</self-uri><abstract><sec><title>Цель исследования</title><p>Цель исследования. Выявление вирусной инфекции слизистой оболочки полости рта у лиц с зубными протезами.</p><p>Материал и методы исследования. Обследовано 110 больных со съемными и 100 – с несъёмными протезами. Диагностика вирусной инфекции проводилась методами ИФА и ПЦР (Квант-21).</p><p>Результаты исследования и их обсуждение. Выявлено, что у больных со съемными протезами заболевания СОПР выявляются у 91 (82,7%) лиц, а с несъемными – у 75 (75,0%) пациентов. Вирусная инфекция у больных со съемными протезами выявляется у 58 (63,7%;91), а с несъемными протезами – у 43 (57,3%; 75) больных. Среди больных со съемными протезами 11 и 16 типы ВПЧ встречаются в 1,3 раза чаще, чем у больных с несъемными протезами, а ВПЧ 6 типа - в 4,6 раз реже. Наиболее часто ВПЧ 11 и 16 типа выявляются у больных, пользующихся съемными протезами при красном плоском лишае, а в группе больных с несъемными протезами они чаще наблюдаются у больных, страдающих пародонтозом.</p></sec><sec><title>Заключение</title><p>Заключение. Вирусная инфекция играет важную роль в развитии заболеваний СОПР, которые отличаются в зависимости от наличия съемных и несъемных зубных конструкций. Наиболее выраженное влияние на течение заболеваний СОПР оказывает папилломавирусная инфекция 6, 11 и 16 типов.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Aim</title><p>Aim. To detect viral infection of the oral mucous membrane in individuals with dentures.</p></sec><sec><title>Material and methods</title><p>Material and methods. 110 patients with removable and 100 - with fixed prostheses were examined. Diagnostics of virus infection were carried out by ELISA and PCR methods (Kvant-21).</p></sec><sec><title>Results and discussion</title><p>Results and discussion. It has been revealed that patients with removable prostheses revealed oral mucosa diseases in 91 (82,7%) persons and with fixed prostheses - in 75 (75,0%) patients. Viral infection in patients with removable dentures is detected in 58 (63.7%;91) and with fixed dentures in 43 (57.3%;75) patients. Among patients with removable dentures, HPV types 11 and 16 occur 1.3 times more frequently than in patients with fixed dentures, and HPV type 6 - 4.6 times less frequently. HPV types 11 and 16 are most frequently detected in patients with removable prostheses in the case of red lichen planus while in the group of patients with fixed prostheses they are more frequently observed in patients suffering from periodontal disease.</p></sec><sec><title>Conclusion</title><p>Conclusion. Viral infection plays an important role in the development of diseases of the oral mucosa, which differ depending on the presence of removable and fixed dental structures. Papillomavirus types 6, 11, and 16 have the most pronounced effect on the course of oral mucosa diseases.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>слизистые оболочки полости рта</kwd><kwd>вирусная инфекция</kwd><kwd>съемные протезы</kwd><kwd>несъемные протезы</kwd><kwd>герпесвирусы</kwd><kwd>папилломавирусы</kwd></kwd-group><kwd-group xml:lang="en"><kwd>oral mucous membranes</kwd><kwd>viral infection</kwd><kwd>removable dentures</kwd><kwd>fixed dentures</kwd><kwd>herpesviruses</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Акмалова Г.М. Роль герпесвирусов в этиопатогенезе красного плоского лишая и хронического рецидивирующего афтозного стоматита с локализацией на слизистой оболочке рта / Г.М. Акмалова, Н.Д. Чернышева // Уральский медицинский журнал. - 2013. - № 5 (110) - С. 27-29.</mixed-citation><mixed-citation xml:lang="en">Akmalova G.M. 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