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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">thealth</journal-id><journal-title-group><journal-title xml:lang="ru">Здравоохранение Таджикистана</journal-title><trans-title-group xml:lang="en"><trans-title>Health care of Tajikistan</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0514-2415</issn><publisher><publisher-name>Редакция журнала «Здравоохранение Таджикистана»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.52888/0514-2515-2024-363-4-47-53</article-id><article-id custom-type="elpub" pub-id-type="custom">thealth-601</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group></article-categories><title-group><article-title>Перинатальные исходы у женщин с поздними самопроизвольными преждевременными родами в зависимости от срока  гестации</article-title><trans-title-group xml:lang="en"><trans-title>Perinatal outcomes in women with late spontaneous preterm birth  depending on gestational age</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ишан-Ходжаева</surname><given-names>Ф. Р.</given-names></name><name name-style="western" xml:lang="en"><surname>Ishan-Khodjaeva</surname><given-names>F. R.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ишан-Ходжаева Фарангис Рустамовна - к.м.н., научный сотрудник акушерского отдела </p></bio><bio xml:lang="en"><p>Ishan-Khodjaeva Farangis Rustamovna - Candidate of medical sciences, researcher of the obstetric department </p></bio><email xlink:type="simple">kachyona@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сармисокова</surname><given-names>Х. Дж.</given-names></name><name name-style="western" xml:lang="en"><surname>Sarmisokova</surname><given-names>H. J.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Рахматуллоева</surname><given-names>Д. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Rakhmatulloeva</surname><given-names>D. M.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ГУ «Таджикский научно-исследовательский институт акушерства, гинекологии и перинатологии»</institution><country>Таджикистан</country></aff><aff xml:lang="en"><institution>SI “Tajik Scientific Research Institute of Obstetrics, Gynecology, and Perinatology”</institution><country>Tajikistan</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>07</day><month>02</month><year>2025</year></pub-date><volume>0</volume><issue>4</issue><fpage>47</fpage><lpage>53</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Ишан-Ходжаева Ф.Р., Сармисокова Х.Д., Рахматуллоева Д.М., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Ишан-Ходжаева Ф.Р., Сармисокова Х.Д., Рахматуллоева Д.М.</copyright-holder><copyright-holder xml:lang="en">Ishan-Khodjaeva F.R., Sarmisokova H.J., Rakhmatulloeva D.M.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.zdrav.tj/jour/article/view/601">https://www.zdrav.tj/jour/article/view/601</self-uri><abstract><sec><title>Цель исследования</title><p>Цель исследования. Изучить перинатальные исходы женщин, жительниц Хатлонской области с поздними самопроизвольными преждевременными родами.</p><p>Материал и методы исследования. Обследованы 146 женщин с поздними самопроизвольными преждевременными родами, в зависимости от срока гестации, при котором произошли роды, были разделены на следующие подгруппы: подгруппа А – срок гестации 34 недели+6 дней (27 женщин), подгруппа Б – срок гестации 35 недель+6 дней (51 женщина), подгруппа В – срок гестации 36 недель + 6 дней (68 женщин). Были использованы параметрические и непараметрические методы биологической статистики (критерии Стъюдента и Уитни-Манна).</p><p>Результаты исследования и их обсуждение. Показано, что каждый 5-й новорожденный, от матери с поздними самопроизвольными преждевременными родами, имеет недостаточный вес для гестационного срока, среди которых синдром задержки роста плода диагностирован в 75,8% случаев. Установлено статистически значимое снижение средней оценки Апгар новорожденных, от матерей с родами на сроке гестации 34+6 на 1-й минуте и 5-й минуте. Дыхательная недостаточность явилась причиной ранней неонатальной смертности в 56,3% случаев. В структуре причин ранней неонатальной заболеваемости дыхательная недостаточность занимает ведущую позицию, частота и степень тяжести которой зависят от срока гестации. Выявлена сильная обратная корреляционная связь между гестационным возрастом и частотой дыхательной недостаточности в раннем неонатальном периоде у новорожденных матерей с поздними самопроизвольными преждевременными родами и синдром задержки роста плода.</p></sec><sec><title>Заключение</title><p>Заключение. Целесообразно в дальнейшем провести исследования, касающиеся эффективности дифференцированных подходов проведения профилактики респираторного дистресс синдрома при поздних преждевременных родах.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Aim</title><p>Aim. To study the perinatal outcomes of women, living in the Khatlon region with late spontaneous preterm birth (LSPB).</p></sec><sec><title>Material and methods</title><p>Material and methods. 146 women with late spontaneous preterm birth were studied, according to the gestational age at which the birth occurred: subgroup A - gestational age 34 weeks + 6 days (27 women), subgroup B - gestational age 35 weeks + 6 days (51 women), subgroup B – gestational period 36 weeks + 6 days (68 women). Parametric and nonparametric methods of biological statistics (Student and Whitney-Munny tests).</p></sec><sec><title>Results</title><p>Results. One in five newborns born to mothers with late spontaneous preterm labour was found to be small for gestational age, with fetal growth restriction diagnosed in 75.8% of these cases. A statistically significant reduction in mean Apgar scores at 1 and 5 minutes was observed in neonates born at 34+6 weeks’ gestation. Respiratory failure was the cause of early neonatal mortality in 56.3% of cases. In the structure of early neonatal morbidity, respiratory failure is a leading cause, with its frequency and severity depending on gestational age. A strong inverse correlation was found between gestational age and the incidence of respiratory failure in the early neonatal period in neonates born to mothers with late spontaneous preterm labour and fetal growth restriction.</p></sec><sec><title>Conclusion</title><p>Conclusion. It is advisable to further conduct research on the effectiveness of differentiated approaches to preventing respiratory distress syndrome in late preterm birth.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>поздние самопроизвольные преждевременные роды</kwd><kwd>синдром задержки роста плода</kwd><kwd>перинатальная смертность</kwd><kwd>перинатальная заболеваемость</kwd><kwd>дыхательная недостаточность</kwd></kwd-group><kwd-group xml:lang="en"><kwd>late spontaneous preterm birth</kwd><kwd>fetal growth restriction syndrome</kwd><kwd>perinatal mortality</kwd><kwd>perinatal morbidity</kwd><kwd>respiratory insufficiency</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Туманова У.Н. Респираторный дистресссиндром как причина ранней неонатальной смертности / У.Н. Туманова, А.И. Щеголев, М.П. Шувалова, Д.Н. 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