thealthЗдравоохранение ТаджикистанаHealth care of Tajikistan0514-2415Редакция журнала «Здравоохранение Таджикистана»10.52888/0514-2515-2025-364-1-22-28thealth-621Research ArticleСтатьиПрогностическая значимость клиренса лактата крови в раннем послеоперационном периоде у пожилых пациентов с метаболическим синдромомPrognostic significance of blood lactate clearance in the early postoperative period in elderly patients with metabolic syndromeГалеевИ. Р.GaleevI. R.

Галеев Ильдар Рафаэлевич - ассистент кафедры анестезиологии и реаниматологии

Уфа

Тел.: +79373181895

Galeev Ildar Rafaelevich Galeev - Assistant of the department of anesthesiology and reanimatology

Ufa

Tel.: +79373181895

ildargaleev@inbox.ruИкромиТ. Ш.IkromiT. Sh.

Душанбе

Dushanbe

СапроновД. Н.SapronovD. N.

Уфа

Ufa

МироновП. И.MironovP. I.

Уфа

Ufa

ФГБОУ ВО «Башкирский государственный медицинский университет» МЗ РФРоссияFSBEI HE Bashkir State Medical University of the Ministry of Health of the Russian FederationRussian FederationГОУ «Институт последипломного образования в сфере здравоохранения» РТТаджикистанSEI Institute of Postgraduate Education in Healthcare of the Republic of TajikistanTajikistan202507042025012228Copyright © Галеев И.Р., Икроми Т.Ш., Сапронов Д.Н., Миронов П.И., 20252025Галеев И.Р., Икроми Т.Ш., Сапронов Д.Н., Миронов П.И.Galeev I.R., Ikromi T.S., Sapronov D.N., Mironov P.I.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.zdrav.tj/jour/article/view/621Цель исследования

Цель исследования. Оценка ассоциированности клиренса лактата крови с послеоперационными осложнениями у пожилых пациентов с метаболическим синдромом.

Материал и методы исследования. Проведено ретроспективное, контролируемое, одноцентровое наблюдательное исследование. 76 пациентов были разделены на группу с метаболическим синдромом (n = 38) и группу сравнения (n = 38).

Результаты исследования и их обсуждение. Частота послеоперационных осложнений было значимо больше в группе больных с метаболическим синдромом (р = 0,005). Длительность лечения в отделении интенсивной терапии была значимо выше у пациентов с метаболическим синдромом. Концентрация лактата была статистически значимо выше в группе с метаболическим синдромом на момент госпитализации в отделение интенсивной терапии и в первые 24 часа после операции при значимо более низком уровне его клиренса.

Выводы

Выводы. У пациентов с метаболическим синдромом отмечается более высокая частота периоперационных нежелательных событий и более длительное послеоперационное лечение. Это ассоциировано с более высоким уровнем лактата крови, что свидетельствует о целесообразности его мониторинга у данного контингента больных.

Aim

Aim. To evaluate the association of blood lactate clearance with postoperative complications in elderly patients with metabolic syndrome.

Materials and methods

Materials and methods. The study was designed as a retrospective, controlled, single-center, observational study in which seventy-six patients were divided into a metabolic syndrome group (n = 38) and a comparison group (n = 38).

Results and discussion

Results and discussion. It was found that the incidence of postoperative complications was significantly higher in the metabolic syndrome group (p = 0.005). In addition, the length of stay in the ICU was significantly longer in patients with metabolic syndrome. Lactate concentrations were also statistically significantly higher in the metabolic syndrome group at the time of admission to the ICU and during the first 24 hours after surgery, associated with a significantly lower lactate clearance rate.

Conclusion

Conclusion: Patients with metabolic syndrome experience a higher frequency of perioperative adverse events and require longer postoperative treatment. This is associated with elevated blood lactate levels, highlighting the importance of lactate monitoring in this patient group

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The authors declare that there are no conflicts of interest present.