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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">thealth</journal-id><journal-title-group><journal-title xml:lang="ru">Здравоохранение Таджикистана</journal-title><trans-title-group xml:lang="en"><trans-title>Health care of Tajikistan</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0514-2415</issn><publisher><publisher-name>Редакция журнала «Здравоохранение Таджикистана»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.52888/0514-2515-2025-366-3-60-66</article-id><article-id custom-type="elpub" pub-id-type="custom">thealth-674</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL ARTICLES</subject></subj-group></article-categories><title-group><article-title>Влияние медикаментозного лечения на качество жизни при воспалительных заболеваниях кишечника: опыт применения опросника IBDQ</article-title><trans-title-group xml:lang="en"><trans-title>The impact of medicinal treatment on quality of life in inflammatory bowel diseases: experience with the IBDQ questionnaire</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4204-5381</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Рахмонов</surname><given-names>Дж. Т.</given-names></name><name name-style="western" xml:lang="en"><surname>Rakhmonov</surname><given-names>J. T.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Рахмонов Джамолиддин Туймуродович - ассистент кафедры </p><p>г. Душанбе </p></bio><bio xml:lang="en"><p>Rakhmonov Jamoliddin Tuymurodovich - assistant </p><p>Dushanbe </p></bio><email xlink:type="simple">djamol8688@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3327-0459</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Джамолова</surname><given-names>Р. Дж.</given-names></name><name name-style="western" xml:lang="en"><surname>Dzhamolova</surname><given-names>R. D.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Джамолова Рухшона Джалолидиновна - кандидат медицинских наук, доцент </p><p>г. Душанбе, Тел.: +992918724088 </p></bio><bio xml:lang="en"><p>Dzhamolova Rukhshona Dzhalolidinovna - Candidate of Medical Sciences, Associate Professor </p><p>Dushanbe, Tel.: +992918724088 </p></bio><email xlink:type="simple">ruha13@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0006-7417-104X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Расулов</surname><given-names>У. Р.</given-names></name><name name-style="western" xml:lang="en"><surname>Rasulov</surname><given-names>U. R.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Расулов Усмон Расулович - доктор медицинских наук, профессор </p><p>г. Душанбе </p></bio><bio xml:lang="en"><p>Rasulov Usmon Rasulovich - Doctor of Medical Sciences, Professor  </p><p>Dushanbe </p></bio><email xlink:type="simple">ruha13@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2456-7509</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Али-Заде</surname><given-names>С. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Ali-Zade</surname><given-names>S. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Али-Заде Сухроб Гаффарович - кандидат медицинских наук, доцент </p><p>г. Душанбе </p></bio><bio xml:lang="en"><p>Ali-Zade Sukhrob Gaffarovich -Candidate of Medical Sciences, Associate Professor </p><p>Dushanbe </p></bio><email xlink:type="simple">suhrob_a@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Кафедра внутренних болезней №3 ГОУ ТГМУ им. Абуали ибни Сино</institution><country>Таджикистан</country></aff><aff xml:lang="en"><institution>Department of Internal Medicine N.3, SEI Avicenna Tajik State Medical University</institution><country>Tajikistan</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>14</day><month>10</month><year>2025</year></pub-date><volume>0</volume><issue>3</issue><fpage>60</fpage><lpage>66</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Рахмонов Д.Т., Джамолова Р.Д., Расулов У.Р., Али-Заде С.Г., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Рахмонов Д.Т., Джамолова Р.Д., Расулов У.Р., Али-Заде С.Г.</copyright-holder><copyright-holder xml:lang="en">Rakhmonov J.T., Dzhamolova R.D., Rasulov U.R., Ali-Zade S.G.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.zdrav.tj/jour/article/view/674">https://www.zdrav.tj/jour/article/view/674</self-uri><abstract><p>Цель исследования: оценка качества жизни пациентов с воспалительными заболеваниями кишечника.Материал и методы: выполнено проспективное поперечное исследование, в котором участвовали 46 пациентов, наблюдение осуществлялось в амбулаторных условиях.Результаты: из общего числа обследованных больных (n=46) болезнью Крона страдали 32 (69,6%) пациента, неспецифический язвенный колит был диагностирован у 14 (30,4%) пациентов. Женщин было 25 (54,3%) человек, мужчин – 21 (45,7%). Средний возраст пациентов составлял 47,3 года. Среди пациентов некурящих было 44 (95,7%) человека, наличие в анамнезе хирургического вмешательства по поводу основного заболевания отмечено у 11 (23,9%) пациентов. Комбинированная схема терапии применялась у 20 (43,5%) пациентов, монотерапия - у 21 (45,7%), остальные 5 (10,9%) пациентов не получали лекарственного лечения. У пациентов, принимавших метипред, отмечено значимое улучшение качества жизни.Выводы: наиболее высокие показатели качества жизни наблюдались у пациентов, получавших метипред. Других статистически значимых корреляций с качеством жизни выявлено не было.</p></abstract><trans-abstract xml:lang="en"><p>Objective: To evaluate quality of life in patients with inflammatory bowel disease.Materials and methods: A prospective cross-sectional study involving 46 patients was conducted with outpatient follow-up.Results: Crohn’s disease was present in 32 (69.6%) of the total number of patients assessed (n = 46), and ulcerative colitis in 14 (30.4%). Of these patients, 25 (54.3%) were women and 21 (45.7%) were men. The mean patient age was 47.3 years. Non-smokers comprised 95.7% of participants. A history of surgery for the primary disease was noted in 11 patients (23.9%). Twenty (43.5%) patients received combination therapy, 21 (45.7%) received monotherapy, and the remaining five (10.9%) did not receive medical treatment. Significant improvement in quality of life was observed among patients treated with metipred.Conclusions: Patients who received Metipred had the highest quality of life scores. No other statistically significant correlations with quality of life were found.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>воспалительные заболевания кишечника</kwd><kwd>болезнь Крона</kwd><kwd>язвенный колит</kwd><kwd>колит</kwd><kwd>качество жизни</kwd></kwd-group><kwd-group xml:lang="en"><kwd>inflammatory bowel disease</kwd><kwd>Crohn’s disease</kwd><kwd>ulcerative colitis</kwd><kwd>colitis</kwd><kwd>quality of life</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Бандель В.Е., Михайлова Е.И., Трофимова Н.В. Качество жизни и психоэмоциональные нарушения как критерий эффективности терапии у пациентов с язвенным колитом. 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