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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">thealth</journal-id><journal-title-group><journal-title xml:lang="ru">Здравоохранение Таджикистана</journal-title><trans-title-group xml:lang="en"><trans-title>Health care of Tajikistan</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0514-2415</issn><publisher><publisher-name>Редакция журнала «Здравоохранение Таджикистана»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.52888/0514-2515-2025-367-4-61-66</article-id><article-id custom-type="elpub" pub-id-type="custom">thealth-692</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL ARTICLES</subject></subj-group></article-categories><title-group><article-title>Значение эластографии селезенки в диагностике портальной гипертензии</article-title><trans-title-group xml:lang="en"><trans-title>Significance of spleen elastography in diagnosis of portal hypertension</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0005-2450-024X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Наимова</surname><given-names>Ш. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Naimova</surname><given-names>Sh. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Наимова Шоира Саидовна – соискатель</p><p>Душанбе</p></bio><bio xml:lang="en"><p>Naimova Shoira Saidovna – the applicant</p><p>Dushanbe</p></bio><email xlink:type="simple">dr.shoira.87@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6619-5168</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Авезов</surname><given-names>С. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Avezov</surname><given-names>S. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Авезов Сайфулло Абдуллоевич – старший научный сотрудник, доктор медицинских наук</p><p>Душанбе</p></bio><bio xml:lang="en"><p>Avezov Sayfullo Abdulloevich - is a senior researcher, Doctor of Medical Sciences</p><p>Dushanbe</p></bio><email xlink:type="simple">saifullo_avezov@rambler.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0003-4799-0689</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ишанкулова</surname><given-names>Д. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Ishankulova</surname><given-names>D. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ишанкулова Дилором Мухамеджановна - старший научный сотрудник, кандидат медицинских наук</p><p>Душанбе</p></bio><bio xml:lang="en"><p>Ishankulova Dilorom Muhamedjanovna - is a senior researcher, Candidate of Medical Sciences</p><p>Dushanbe</p></bio><email xlink:type="simple">i.dilorom@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ГУ «Институт гастроэнтерологии Республики Таджикистан»</institution><country>Таджикистан</country></aff><aff xml:lang="en"><institution>SI Institute of Gastroenterology of the Republic of Tajikistan</institution><country>Tajikistan</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>24</day><month>01</month><year>2026</year></pub-date><volume>0</volume><issue>4</issue><fpage>61</fpage><lpage>66</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Наимова Ш.С., Авезов С.А., Ишанкулова Д.М., 2026</copyright-statement><copyright-year>2026</copyright-year><copyright-holder xml:lang="ru">Наимова Ш.С., Авезов С.А., Ишанкулова Д.М.</copyright-holder><copyright-holder xml:lang="en">Naimova S.S., Avezov S.A., Ishankulova D.M.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.zdrav.tj/jour/article/view/692">https://www.zdrav.tj/jour/article/view/692</self-uri><abstract><sec><title>Цель</title><p>Цель: изучение значений ультразвуковой эластографии селезенки в диагностике портальной гипертензии.</p></sec><sec><title>Материал и методы</title><p>Материал и методы: изучено значение эластографии селезенки в качестве неинвазивного маркера диагностики, прогнозирования и необходимости лечения портальной гипертензии. Обследованы 33 больных (18 мужчин и 15 женщин, средний возраст 48,47±1,97 лет) циррозом печени (ЦП). У 23 больных причиной ЦП был вирус гепатита В, у 10 – вирус гепатита С. Эластография печени и селезенки проводились на аппарате FibroScan. У 15 (45,4%) больных диагностирован ЦП класса А по Чайлд-Пью, у 7 (21,2%) — класса В и у 11 (33,3%) — класса С. Общий средний балл шкалы Чайлд-Пью составил 8,24±1,6. Варикозное расширение вен пищевода (ВРВП) у 12 больных было I степени, у 5 – II степени, у 6 – III степени и у 7 – YI степени. У троих пациентов ВРВП при эндоскопии отсутствовало. Большие варикозные узлы диагностированы у 18 больных, что составляет 55% от общего числа. У здоровых показатель эластографии селезенки (ПЭС) варьировались от 8 до 24 кПа, а у больных ЦП от 18 до 75 кПа. ПЭС был достоверно выше у пациентов с большими узлами по сравнению с пациентами с маленькими или отсутствием варикоза (61,91±2,94 против 43,72±3,35; р &lt;0,05), что указывает на эффективность эластографии при выявлении больших ВРВП. Многофакторный анализ демонстрировал, что спленомегалия, расширение воротной и селезеночной вен, снижение количества тромбоцитов в периферической крови и эластометрия селезенки могут быт предикторами кровотечения из ВРВП.</p></sec><sec><title>Результаты</title><p>Результаты: ПЭС является эффективным методом для выявления больших варикозных вен с риском кровотечения и дополняет другие неинвазивные методы, играющие роль в скрининге ВРВП у пациентов ЦП.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Objective</title><p>Objective: to evaluate the significance of spleen ultrasound elastography in the diagnosis of portal hypertension.</p></sec><sec><title>Material and methods</title><p>Material and methods: thirty-three patients (18 men and 15 women, mean age 48.47±1.97 years) with liver cirrhosis were examined. In 23 cases, the cause of cirrhosis was hepatitis B virus, while 10 patients had hepatitis C virus as the cause. Liver and spleen elastography were performed using FibroScan. Child-Pugh class A was diagnosed in 15 patients (45.4%), class B in seven patients (21.2%), and class C in 11 patients (33.3%); the mean Child-Pugh score was 8.24 ± 1.6. Esophageal varices were grade I in 12 patients, grade II in five, grade III in six, and grade IV in seven; varices were absent on endoscopy in three patients. Large varices were present in 18 patients (55%). Spleen stiffness values ranged from 8 to 24 kPa in healthy individuals and from 18 to 75 kPa in patients with cirrhosis. Spleen stiffness was significantly higher in patients with large varices than in those with small varices or no varices (61.91 ± 2.94 kPa vs. 43.72 ± 3.35 kPa; p &lt; 0.05), which supports the use of elastography in the detection of large esophageal varices. Multivariable analysis indicated that splenomegaly, dilatation of the portal and splenic veins, decreased peripheral platelet count and spleen elastography may predict bleeding from esophageal varices.</p></sec><sec><title>Results</title><p>Results: spleen stiffness measurement is an effective method for identifying large varices at risk of bleeding and complements other noninvasive methods used in screening for esophageal varices in patients with liver cirrhosis.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>цирроз печени</kwd><kwd>портальная гипертензия</kwd><kwd>эластография селезенки</kwd></kwd-group><kwd-group xml:lang="en"><kwd>liver cirrhosis</kwd><kwd>portal hypertension</kwd><kwd>spleen elastography</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Mazur R., Celmer M., Silicki J. et al. Clinical applications of spleen ultrasound elastography – a review. 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