thealthЗдравоохранение ТаджикистанаHealth care of Tajikistan0514-2415Редакция журнала «Здравоохранение Таджикистана»10.52888/0514-2515-2026-368-1-146-160thealth-723Research ArticleОБЗОР ЛИТЕРАТУРЫREVIEWРябчик Эдуарда (Fritillaria Eduardii) – эндемик центральной Азии: фитохимия, фармакогнозия и фармакологические перспективыFritillaria Eduardii – endemic to central asia: phytochemistry, pharmacognosy, and pharmacological prospectshttps://orcid.org/0009-0009-4244-9723МуродоваН. М.MurodovaN. M.

Муродова Нушина Махмадовна — аспирантка ТГМУ имени Абуали ибни Сино; младший научный сотрудник ГУ «Научно-исследовательского фармацевтического центра» Министерство здравоохранение и социальной защиты население Республики Таджикистан

г. Душанбе

тел.: +992933555570

Murodova Nushina Mahmadovna - Postgraduate student at Avicenna Tajik State Medical University; Junior Researcher at the State Institution “Research Pharmaceutical Center” of the Ministry of Health and Social Protection of the Population of the Republic of Tajikistan

Dushanbe

tel.: +992933555570

mnushina1990@gmail.comhttps://orcid.org/0000-0002-1442-9508ЮсуфиС. Дж.YusufiS. J.

Юсуфи Саломуддин Джаббор - д.ф.н, профессор, академик Национальной академии наук Таджикистана, Первый заместитель министра здравоохранения и социальной защиты населения Республики Таджикистан

Душанбе

Yusufi Salomudin Jabor - Doctor of Pharmaceutical Sciences, Professor, Academician of the National Academy of Sciences of Tajikistan; First Deputy Minister of Health and Social Protection of the Republic of Tajikistan

Dushanbe

salomudin@mail.ruhttps://orcid.org/0000-0002-0133-8279ИмомиёнР.ImomiyonR.

Имомиён Равшан – кандидат химических наук, ученый секретарь

г. Душанбе

Imomiyon Ravshan – Candidate of Chemical Sciences, Scientific Secretary

Dushanbe

tudacavsh@yandex.ruhttps://orcid.org/0000-0002-0829-9364БобокалоновДж. Т.BobokalonovJ. T.

Бобокалонов Джамшед Толехмуродович - ведущий научный сотрудник, кандидат биологических наук

Душанбе

Bobokalonov Jamshed Tolehmurodovich - Senior Researcher, Candidate of Biological Sciences

Dushanbe

jamshedbt@gmail.comКафедра Фармацевтической Технологии имени профессора Халифаева Д.Р., ГОУ Таджикский государственный медицинский университет имени Абуали ибни Сино; ГУ «Научно-исследовательский фармацевтический центр» МЗ и СЗН РТТаджикистанDepartment of Pharmaceutical Technology named after рrofessor D.R. Khalifaev, SEI Avicenna Tajik State Medical University; SI Scientific Research Pharmaceutical Center of the Ministry of Health and Social Protection of the Republic of ajikistanTajikistanГУ «Научно-исследовательский фармацевтический центр» МЗ и СЗН РТРоссияSI Scientific Research Pharmaceutical Center of the Ministry of Health and Social Protection of the Republic of TajikistanRussian FederationНациональной академии наук Республики Таджикистан, Институт химии им. В.И. НикитинаТаджикистанSI National Academy of Sciences of the Republic of Tajikistan, Institute of Chemistry named after V.I. NikitinaTajikistan20261504202601146160Copyright © Муродова Н.М., Юсуфи С.Д., Имомиён Р., Бобокалонов Д.Т., 20262026Муродова Н.М., Юсуфи С.Д., Имомиён Р., Бобокалонов Д.Т.Murodova N.M., Yusufi S.J., Imomiyon R., Bobokalonov J.T.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.zdrav.tj/jour/article/view/723

В настоящем обзоре систематизированы современные научные данные о Fritillaria eduardii (Рябчик Эдуарда) — эндемичном растении Центральной Азии, широко распространённом в различных регионах Таджикистана. Этот вид является декоративным и обладает значительным фармацевтическим потенциалом. Изучение его фармакологических свойств и биологически активных соединений важно для науки и разработки новых лекарственных форм. Традиционно его луковицы используются в народной медицине, однако фармакогностическая характеристика вида, произрастающего на территории Таджикистана, пока недостаточно исследована.

Цель данного обзора — на основе публикаций за период 2020–2025 гг. обобщить современные данные по Fritillaria eduardii, включая этноботанические исследования, ботаническую характеристику, химический состав, интродукцию, а также сведения о других видах рода Fritillaria и их сравнительный химический анализ с Fritillaria eduardii. Основное внимание уделено анализу фитохимического состава F. eduardii, в котором преимущественно доминируют изостероидные алкалоиды и флавоноиды с разнообразной биологической активностью. Особое внимание уделено проблемам идентификации, стандартизации сырья и необходимости охраны этого редкого вида.

This review systematizes current scientific data on Fritillaria eduardii, an endemic plant of Central Asia widespread in various regions of Tajikistan. This species is ornamental and has significant pharmaceutical potential. Studying its pharmacological properties and biologically active compounds is important for science and the development of new dosage forms. Its bulbs are traditionally used in folk medicine; however, the pharmacognostic characteristics of this species, which grows in Tajikistan, remain insufficiently studied.

The objective of this review is to summarize current data on Fritillaria eduardii, based on publications from the 2020 – 2025 period, including ethnobotanical studies, botanical characteristics, chemical composition, introduction, as well as information on other species of the genus Fritillaria and their comparative chemical analysis with Fritillaria eduardii.

This article focuses on the analysis of the phytochemical composition of F. eduardii, which is dominated by isosteroidalalkaloids and flavonoids with diverse biological activity. Particular attention is given to the issues of identification,standardization of raw materials, and the need to protect this rare species.

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The authors declare that there are no conflicts of interest present.