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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">thealth</journal-id><journal-title-group><journal-title xml:lang="ru">Здравоохранение Таджикистана</journal-title><trans-title-group xml:lang="en"><trans-title>Health care of Tajikistan</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0514-2415</issn><publisher><publisher-name>Редакция журнала «Здравоохранение Таджикистана»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.52888/0514-2515-2026-369-2-109-114</article-id><article-id custom-type="elpub" pub-id-type="custom">thealth-745</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL ARTICLES</subject></subj-group></article-categories><title-group><article-title>Результаты синустрабекулэктомии с одномоментной лазерной циклокоагуляцией в микропульсовом режиме у пациентов с закрытоугольной глаукомой</article-title><trans-title-group xml:lang="en"><trans-title>Results of sinustrabeculectomy with simultaneous laser cyclocoagulation in micropulse mode in patients with angle-closure glaucoma</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0007-4241-2635</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Холматов</surname><given-names>С. Х.</given-names></name><name name-style="western" xml:lang="en"><surname>Kholmatov</surname><given-names>S. Kh.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Саидджафар Хилолович Холматов - аспирант</p><p>тел.: +992927609060</p><p>Худжанд</p><p>Душанбе </p></bio><bio xml:lang="en"><p>Saidjafar Khilolovich Kholmatov - postgraduate student</p><p>tel.: +992927609060</p><p>Dushanbe </p></bio><email xlink:type="simple">kholmatovs@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3922-3829</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Карим-заде</surname><given-names>Х. Дж.</given-names></name><name name-style="western" xml:lang="en"><surname>Karim-zade</surname><given-names>Kh. J.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Карим-Заде Хакима Джанговаровна- кандидат медицинских наук, доцент  </p><p>Душанбе </p></bio><bio xml:lang="en"><p>Karim-Zade Khakima Jangovarovna - candidate of Medical Sciences, Associate Professor</p><p>Dushanbe </p></bio><email xlink:type="simple">kh.karimzade@gmail.com</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8292-8344</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Махмадзода</surname><given-names>Ш. К.</given-names></name><name name-style="western" xml:lang="en"><surname>Makhmadzoda</surname><given-names>Sh. K.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Махмадзода Шамсулло Курбон - к.м.н, доцент., зав. кафедрой  </p><p>Душанбе </p></bio><bio xml:lang="en"><p>Makhmadzoda Shamsullo Kurbon - Ph.D., Associate Professor, Head of the Department of Ophthalmology</p><p>Dushanbe </p></bio><email xlink:type="simple">shamsullo-@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Клиника «Босира»;&#13;
Кафедра офтальмологии, ГОУ «ТГМУ им. Абуали ибни Сино»</institution><country>Таджикистан</country></aff><aff xml:lang="en"><institution>Eye clinic «Bosira»;&#13;
Department of Ophthalmology SEI Avicenna Tajik State Medical University</institution><country>Tajikistan</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Кафедра офтальмологии, ГОУ «ТГМУ им. Абуали ибни Сино»</institution><country>Таджикистан</country></aff><aff xml:lang="en"><institution>Department of Ophthalmology SEI Avicenna Tajik State Medical University</institution><country>Tajikistan</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2026</year></pub-date><pub-date pub-type="epub"><day>02</day><month>07</month><year>2026</year></pub-date><volume>0</volume><issue>2</issue><fpage>109</fpage><lpage>114</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Холматов С.Х., Карим-заде Х.Д., Махмадзода Ш.К., 2026</copyright-statement><copyright-year>2026</copyright-year><copyright-holder xml:lang="ru">Холматов С.Х., Карим-заде Х.Д., Махмадзода Ш.К.</copyright-holder><copyright-holder xml:lang="en">Kholmatov S.K., Karim-zade K.J., Makhmadzoda S.K.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.zdrav.tj/jour/article/view/745">https://www.zdrav.tj/jour/article/view/745</self-uri><abstract><sec><title>Цель</title><p>Цель: дать оценку эффективности и безопасности одномоментного проведения синустрабекулэктомии и лазерной циклокоагуляции в микропульсовом режиме у пациентов с закрытоугольной глаукомой.</p></sec><sec><title>Материал и методы</title><p>Материал и методы: проведён анализ эффективности и безопасности синустрабекулэктомии (СТЭ) (25 глаз) и одномоментного выполнения синустрабекулэктомии в сочетании с лазерной циклокоагуляцией в микропульсовом режиме (мЛЦК) (25 глаз) у пациентов с хронической закрытоугольной глаукомой при сроке наблюдения 12 месяцев.</p></sec><sec><title>Результаты</title><p>Результаты: после СТЭ уровень ВГД снизился с 28,2±5,8 мм рт.ст. до 23,7±7,0 мм рт.ст. через 12 месяцев наблюдения, тогда как после СТЭ в сочетании с одномоментной мЛЦК - с 30,6±6,7 мм рт.ст. до 20,2±3,2 мм рт.ст. После операции гипотензивная терапия потребовалась в 7 из 25 (28%) глаз основной группы и в 12 из 25 (48%) глаз контрольной группы (p&lt;0,05). Случаев развития стойкой гипотонии, послеоперационного иридоциклита, гипертензии вследствие блокады фистулы, а также субатрофии глазного яблока не зарегистрировано.</p></sec><sec><title>Заключение</title><p>Заключение: одномоментное проведение синустрабекулэктомии и лазерной циклокоагуляции в микропульсовом режиме является более эффективным и безопасным методом лечения закрытоугольной глаукомы</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Objective</title><p>Objective: To evaluate the efficacy and safety of sinustrabeculectomy (STE) and simultaneous micropulse laser cyclocoagulation (mLCC) in patients with angle-closure glaucoma.</p></sec><sec><title>Material and Methods</title><p>Material and Methods: Data regarding the efficacy and safety of STE (25 eyes) and simultaneous STE and mLCC (25 eyes) in patients with chronic angle-closure glaucoma with a follow-up period of 12 months were analyzed.</p></sec><sec><title>Results</title><p>Results: After STE, the Intraocular Pressure (IOP) decreased from 28.2±5.8 mmHg to 23.7±7.0 mmHg after 12 months. After STE with simultaneous mLCC the IOP decreased from 30.6±6.7 mmHg to 20.2±3.2 mmHg. After surgery, antihypertensive drugs were prescribed in 7 of 25 (28%) eyes of the main group, and in 12 of 25 eyes (48%) (p&lt;0.05) of the control group. There were no cases of persistent hypotension, postoperative iridocyclitis, ocular hypertension with ostium blockage, or phthisis bulbi.</p></sec><sec><title>Conclusions</title><p>Conclusions: STE with a simultaneous mLCC is a more effective and safer method of treating angle-closure glaucoma.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>глаукома</kwd><kwd>лазерная циклокоагуляция</kwd><kwd>микропульсовой режим</kwd><kwd>внутриглазное давление</kwd></kwd-group><kwd-group xml:lang="en"><kwd>glaucoma</kwd><kwd>laser cyclocoagulation</kwd><kwd>micropulse mode</kwd><kwd>intraocular pressure</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Егоров В.В., Поступаев А.В., Поступаева Н.В. Результаты применения микроимпульсной циклофотокоагуляции в лечении пациентов с первичной открытоугольной глаукомой. Клиническая офтальмология. 2022;22(4):204-209.</mixed-citation><mixed-citation xml:lang="en">Egorov V.V., Postupaev A.V., Postupaev N.V. Results of the use of microimpulse cyclophotocoagulation in the treatment of patients with primary openangle glaucoma. Clinical ophthalmology. 2022;22(4):204-209.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Aung T., Tow S.L., Yap E.Y., et al. Trabeculectomy for acute primary angle closure. Ophthalmology. 2000;107:1298-1302.</mixed-citation><mixed-citation xml:lang="en">Aung T., Tow S.L., Yap E.Y., et al. Trabeculectomy for acute primary angle closure. Ophthalmology. 2000;107:1298-1302.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Cheng J.W., Zong Y., Zeng Y.Y., et al. The prevalence of primary angle closure glaucoma in adult Asians: a systematic review and meta-analysis. PLoS One. 2014;24:e103222.</mixed-citation><mixed-citation xml:lang="en">Cheng J.W., Zong Y., Zeng Y.Y., et al. The prevalence of primary angle closure glaucoma in adult Asians: a systematic review and meta-analysis. PLoS One. 2014;24:e103222.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Day A.C., Baio G., Gazzard G., et al. The prevalence of primary angle closure glaucoma in European derived populations: a systematic review. Br J Ophthalmol. 2012;96:1162-1167.</mixed-citation><mixed-citation xml:lang="en">Day A.C., Baio G., Gazzard G., et al. The prevalence of primary angle closure glaucoma in European derived populations: a systematic review. Br J Ophthalmol. 2012;96:1162-1167.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Fortune B., Choe T.E., Reynaud J., et al. Deformation of the rodent optic nerve head and peripapillary structures during acute intraocular pressure elevation. Invest Ophthalmol Vis Sci. 2011;52:6651-6661.</mixed-citation><mixed-citation xml:lang="en">Fortune B., Choe T.E., Reynaud J., et al. Deformation of the rodent optic nerve head and peripapillary structures during acute intraocular pressure elevation. Invest Ophthalmol Vis Sci. 2011;52:6651-6661.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Ganesh S.K., Rishi K. Necrotizing scleritis following diode laser trans-scleral cyclophotocoagulation. Indian J Ophthalmol. 2006;54:199-200.</mixed-citation><mixed-citation xml:lang="en">Ganesh S.K., Rishi K. Necrotizing scleritis following diode laser trans-scleral cyclophotocoagulation. Indian J Ophthalmol. 2006;54:199-200.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">National Institute for Health and Care Excellence. Glaucoma: diagnosis and management. London, UK; 2017. 31 p.</mixed-citation><mixed-citation xml:lang="en">National Institute for Health and Care Excellence. Glaucoma: diagnosis and management. London, UK; 2017. 31 p.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Kwong Y.Y., Tham C.C., Leung Y., et al. Scleral perforation following diode laser trans-scleral cyclophotocoagulation. Eye. 2006;20:1316-1317.</mixed-citation><mixed-citation xml:lang="en">Kwong Y.Y., Tham C.C., Leung Y., et al. Scleral perforation following diode laser trans-scleral cyclophotocoagulation. Eye. 2006;20:1316-1317.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Lai J.S., Tham C.C., Chan J.C., et al. Diode laser transscleral cyclophotocoagulation as primary surgical treatment for medically uncontrolled chronic angle closure glaucoma: long-term clinical outcomes. J Glaucoma. 2005;14:114-119.</mixed-citation><mixed-citation xml:lang="en">Lai J.S., Tham C.C., Chan J.C., et al. Diode laser transscleral cyclophotocoagulation as primary surgical treatment for medically uncontrolled chronic angle closure glaucoma: long-term clinical outcomes. J Glaucoma. 2005;14:114-119.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Liu W., Chen Y., Lv Y., et al. Diode laser transscleral cyclophotocoagulation followed by phacotrabeculectomy on medically unresponsive acute primary angle closure eyes: the long-term result. BMC Ophthalmol. 2014;14:26.</mixed-citation><mixed-citation xml:lang="en">Liu W., Chen Y., Lv Y., et al. Diode laser transscleral cyclophotocoagulation followed by phacotrabeculectomy on medically unresponsive acute primary angle closure eyes: the long-term result. BMC Ophthalmol. 2014;14:26.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Manna A., Foster P., Papadopoulos M., et al. Cyclodiode laser in the treatment of acute angle closure. Eye. 2012;26:742-745.</mixed-citation><mixed-citation xml:lang="en">Manna A., Foster P., Papadopoulos M., et al. Cyclodiode laser in the treatment of acute angle closure. Eye. 2012;26:742-745.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Rulli E., Biagioli E., Riva I., et al. Efficacy and safety of trabeculectomy vs nonpenetrating surgical procedures: a systematic review and meta-analysis. JAMA Ophthalmol. 2013;131:1573-1582.</mixed-citation><mixed-citation xml:lang="en">Rulli E., Biagioli E., Riva I., et al. Efficacy and safety of trabeculectomy vs nonpenetrating surgical procedures: a systematic review and meta-analysis. JAMA Ophthalmol. 2013;131:1573-1582.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Tan A.M., Chockalingam M., Aquino M.C., et al. Micropulse transscleral diode laser cyclophotocoagulation in the treatment of refractory glaucoma. Clin Exp Ophthalmol. 2010;38:266-272.</mixed-citation><mixed-citation xml:lang="en">Tan A.M., Chockalingam M., Aquino M.C., et al. Micropulse transscleral diode laser cyclophotocoagulation in the treatment of refractory glaucoma. Clin Exp Ophthalmol. 2010;38:266-272.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Zhang S.H., Dong F.T., Mao J., et al. Factors related to prognosis of refractory glaucoma with diode laser transscleral cyclophotocoagulation treatment. Chin Med Sci J. 2011;26:137-140.</mixed-citation><mixed-citation xml:lang="en">Zhang S.H., Dong F.T., Mao J., et al. Factors related to prognosis of refractory glaucoma with diode laser transscleral cyclophotocoagulation treatment. Chin Med Sci J. 2011;26:137-140.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
