thealthЗдравоохранение ТаджикистанаHealth care of Tajikistan0514-2415Редакция журнала «Здравоохранение Таджикистана»10.52888/0514-2515-2026-369-2-141-149thealth-749Research ArticleОБЗОРЫ ЛИТЕРАТУРЫREVIEW ARTICLESВ фокусе внимания повторный инфаркт миокардаFocus on recurrent myocardial infarctionhttps://orcid.org/0009-0009-3815-9758КасироваГ. С.KasirovaG. S.

Касирова Гуландом Саиджоновна – заведующая отделением хронической ишемической болезни сердца ГУ «Республиканский клинический центр кардиологии», соискатель ГУ «Таджикский научно-исследовательский институт профилактической медицины»

тел.: +992917337379

г. Душанбе 

Kasirova Gulandom Saidjonovna – Head of the Department of Chronic Ischemic Heart Disease, State Institution “Republican Clinical Center of Cardiology,” Postgraduate Student, State Institution “Tajik Scientific-Research Institute of Preventive Medicine”  

tel.: +992917337379

Dushanbe 

kasirova89@inbox.ruhttps://orcid.org/0009-0000-8073-6154РаджабзодаМ. Э.RajabzodaM. E.

Раджабзода Музафар Эмом – доктор медицинских наук, директор ГУ «Республиканский клинический центр кардиологии»

г. Душанбе 

Rajabzoda Muzafar Emom – Doctor of Medical Sciences, Director of the State Institution “Republican Clinical Center of Cardiology”  

Dushanbe 

cardio2008@inbox.ruhttps://orcid.org/0009-0000-8278-5697АхмадзодаМ. Ш.AhmadzodaM. Sh.

Ахмадзода Махзариддини Шамол – соискатель ГУ «Таджикский научно-исследовательский институт профилактической медицины», заведующий отделением кардиологии ГУ «Комплекс здоровья Истиклол»

г. Душанбе 

Ahmadzoda Makhzariddini Shamol – Postgraduate Student, State Institution “Tajik Scientific-Research Institute of Preventive Medicine,” Head of the Cardiology Department, State Institution “Istiklol Health Complex”

Dushanbe 

mahzariddinahmadzoda@gmail.comГУ «Республиканский клинический центр кардиологии»; ГУ «Таджикский научно-исследовательский институт профилактической медицины»ТаджикистанSI Republican Clinical Center of Cardiology; SI Tajik Scientific-Research Institute of Preventive MedicineTajikistanГУ «Республиканский клинический центр кардиологии»ТаджикистанSI Republican Clinical Center of CardiologyTajikistanГУ «Таджикский научно-исследовательский институт профилактической медицины»ТаджикистанSI Tajik Scientific-Research Institute of Preventive MedicineTajikistan20260207202602141149Copyright © Касирова Г.С., Раджабзода М.Э., Ахмадзода М.Ш., 20262026Касирова Г.С., Раджабзода М.Э., Ахмадзода М.Ш.Kasirova G.S., Rajabzoda M.E., Ahmadzoda M.S.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.zdrav.tj/jour/article/view/749

Повторный инфаркт миокарда (ПИМ) остается критически значимой проблемой в кардиологии, существенно ухудшающей прогноз и приводящей к высокой смертности (риск до 8%, до трети пациентов умирают в течение года после рецидива). Он также способствует развитию или прогрессированию сердечной недостаточности. Пациенты после острого инфаркта миокарда (ОИМ) сохраняют высокий риск повторных ишемических событий. Цель обзора – систематизация современных подходов к диагностике, профилактике и лечению ПИМ, а также анализ факторов, влияющих на прогноз. Поиск литературы проводился в MEDLINE, PubMed, Scopus и ELIBRARY (2015–2024 гг.) с использованием ключевых слов: «повторный инфаркт миокарда», «острый коронарный синдром», «факторы риска», «реваскуляризация», «чрескожные коронарные вмешательства». Включены релевантные исследования, обзоры и клинические рекомендации.

Recurrent myocardial infarction (RMI) remains a critically important problem in cardiology, significantly worsening patient prognosis and contributing to high mortality rates (with a ris of up to 8%, and up to one-third of patients dying within a year after recurrence). It also contributes to the development or progression of heart failure. Patients following acute myocardial infarction (AMI) retain a high risk of recurrent ischemic events. The objective of this review is to systematize current approaches to the diagnosis, prevention, and treatment of RMI, as well as to analyze factors influencing clinical prognosis. A literature search was conducted in MEDLINE, PubMed, Scopus, and ELIBRARY (2015–2024) using the following keywords: “recurrent myocardial infarction,” “acute coronary syndrome,” “risk factors,” “revascularization,” “percutaneous coronary intervention.” Relevant studies, reviews, and clinical guidelines were included.

повторный инфаркт миокардаострый коронарный синдром (ОКС)факторы рискареваскуляризациячрескожные коронарные вмешательства (ЧКВ)Recurrent myocardial infarctionacute coronary syndrome (ACS)risk factorsrevascularizationpercutaneous coronary intervention (PCI)ReferencesОкругин С.А., Репин А.Н. Заболеваемость, летальность, гендерные и клинико-анамнестические особенности повторного инфаркта миокарда. Клиническая медицина. 2021;99(11–12):627–631.Okrugin S.A., Repin A.N. Morbidity, mortality, gender and clinical-anamnestic features of recurrent myocardial infarction. Klinicheskaya meditsina. 2021;99(11–12):627–631. (In Russ.). DOI: 10.30629/0023-2149-2021-99-11-12-627-631.Salari N, Morddarvanjoghi F, Abdolmaleki A, Rasoulpoor S, Khaleghi AA, Hezarkhani LA, et al. The global prevalence of myocardial infarction: a systematic review and meta-analysis. BMC Cardiovasc Disord. 2023 Apr 22;23(1):206. DOI: 10.1186/s12872-023-03231-w.Salari N, Morddarvanjoghi F, Abdolmaleki A, Rasoulpoor S, Khaleghi AA, Hezarkhani LA, et al. The global prevalence of myocardial infarction: a systematic review and meta-analysis. BMC Cardiovasc Disord. 2023 Apr 22;23(1):206. DOI: 10.1186/s12872-023-03231-w.Косолапов В.П., Ярмонова М.В. Анализ высокой сердечно-сосудистой заболеваемости и смертности взрослого населения как медико-социальной проблемы и поиск путей ее решения. Уральский медицинский журнал. 2021;20(1):58–64.Kosolapov V.P., Yarmonova M.V. Analysis of high cardiovascular morbidity and mortality of the adult population as a medical and social problem and the search for ways to solve it. Ural Medical Journal. 2021;20(1):58–64. (In Russ.). DOI: 10.52420/2071-5943-2021-20-1-58-64.Марцевич С.Ю., Кутишенко Н.П., Сичинава Д.П., Калайджян Е.П., Каспарова Э.А., Загребельный А.В. и др. Основные сердечно-сосудистые осложнения и показатели смертности в течение первых полутора лет после перенесенного острого инфаркта миокарда: данные проспективного амбулаторного регистра ПРОФИЛЬ-ИМ. Рациональная Фармакотерапия в Кардиологии. 2020;16(3):432-438.Martsevich S.Yu., Kutishenko N.P., Sichinava D.P., Kalaydzhyan E.P., Kasparova E.A., Zagrebelnyy A.V., et al. The Main Cardiovascular Complications and Mortality Rates During the First One and a Half Years after Acute Myocardial Infarction: Data from the Prospective Outpatient Registry PROFILE-IM. Rational Pharmacotherapy in Cardiology. 2020;16(3):432-438. (In Russ.). DOI: 10.20996/1819-6446-2020-06-11.Марцевич С.Ю. Повторный инфаркт миокарда — нерешённая проблема доказательной медицины. Кардиоваскулярная терапия и профилактика. 2024;23(6):4019.Martsevich S.Yu. Recurrent myocardial infarction as an unsolved problem of evidence-based medicine. Cardiovascular Therapy and Prevention. 2024;23(6):4019. (In Russ.). DOI: 10.15829/1728-8800-2024-4019.Song J., Murugiah K., Hu S., Gao Y., Li X., Krumholz H.M., et al. Incidence, predictors, and prognostic impact of recurrent acute myocardial infarction in China. Heart. 2020 Sep 16;107(4):313–8. DOI:10.1136/heartjnl-2020-317165.Song J., Murugiah K., Hu S., Gao Y., Li X., Krumholz H.M., et al. Incidence, predictors, and prognostic impact of recurrent acute myocardial infarction in China. Heart. 2020 Sep 16;107(4):313–8. DOI:10.1136/heartjnl-2020-317165.Danchin N. Improved long-term survival after acute myocardial infarction: the success of comprehensive care from the acute stage to the long term. European Heart Journal. 2023 Feb 7;44(6):499-501. DOI:10.1093/eurheartj/ehac714. PMID: 36537121.Danchin N. Improved long-term survival after acute myocardial infarction: the success of comprehensive care from the acute stage to the long term. European Heart Journal. 2023 Feb 7;44(6):499-501. DOI:10.1093/eurheartj/ehac714. PMID: 36537121.Усова Е.И., Малишевский Л.М., Алиева А.С., Макарова Т.А., Алиева М.С., Яковлев А.Н., Конради А.О. Анализ предикторов риска развития повторных острых сердечно-сосудистых событий у пациентов с острым коронарным синдромом. Российский кардиологический журнал. 2024;29(6):5881.Usova E.I., Malishevskiy L.M., Alieva A.S., Makarova T.A., Alieva M.S., Yakovlev A.N., Konradi A.O. Analysis of predictors of recurrent acute cardiovascular events in patients with acute coronary syndrome. Russian Journal of Cardiology. 2024;29(6):5881. (In Russ.). DOI: 10.15829/1560-4071-2024-5881.Thygesen K., Alpert J.S., Jaffe A.S., Chaitman B.R., Bax J.J., Morrow D.A., White H.D.; Executive Group on behalf of the Joint European Society of Cardiology (ESC)/American College of Cardiology (ACC)/American Heart Association (AHA)/World Heart Federation (WHF) Task Force for the Universal Definition of Myocardial Infarction. Fourth Universal Definition of Myocardial Infarction (2018). Circulation. 2018 Nov 13;138(20):e618-e651. DOI: 10.1161/CIR.0000000000000617.Thygesen K., Alpert J.S., Jaffe A.S., Chaitman B.R., Bax J.J., Morrow D.A., White H.D.; Executive Group on behalf of the Joint European Society of Cardiology (ESC)/American College of Cardiology (ACC)/American Heart Association (AHA)/World Heart Federation (WHF) Task Force for the Universal Definition of Myocardial Infarction. Fourth Universal Definition of Myocardial Infarction (2018). Circulation. 2018 Nov 13;138(20):e618-e651. DOI: 10.1161/CIR.0000000000000617.Прудников А.Р., Щупакова А.Н., Коробов Г.Д., и др. Прогнозирование развития повторных сердечно-сосудистых событий в течение года после стентирования коронарных артерий у пациентов с инфарктом миокарда. Новости хирургии. 2020;28(4):377–386.Prudnikov A.R., Shchupakova A.N., Korobov G.D., et al. Prediction of recurrent cardiovascular events within a year after coronary artery stenting in patients with myocardial infarction. Surgery News. 2020;28(4):377–386. (In Russ.). DOI: 10.18484/2305-0047.2020.4.377.Chen D.Y., Li C.Y., Hsieh M.J., Chen C.C., Hsieh I.C., Chen T.H., et al. Predictors of subsequent myocardial infarction, stroke, and death in stable post-myocardial infarction patients: A nationwide cohort study. European Heart Journal Acute Cardiovascular Care. 2019 Oct;8(7):634-642. DOI: 10.1177/2048872617730037.Chen D.Y., Li C.Y., Hsieh M.J., Chen C.C., Hsieh I.C., Chen T.H., et al. Predictors of subsequent myocardial infarction, stroke, and death in stable post-myocardial infarction patients: A nationwide cohort study. European Heart Journal Acute Cardiovascular Care. 2019 Oct;8(7):634-642. DOI: 10.1177/2048872617730037.Abel W.M., Scanlan L.N., Horne C.E., Crane P.B. Factors Associated With Myocardial Infarction Reoccurrence. Journal of Cardiovascular Nursing. 2022;37(4):359-367. DOI: 10.1097/JCN.0000000000000796.Abel W.M., Scanlan L.N., Horne C.E., Crane P.B. Factors Associated With Myocardial Infarction Reoccurrence. Journal of Cardiovascular Nursing. 2022;37(4):359-367. DOI: 10.1097/JCN.0000000000000796.Johansson S., Rosengren A., Young K., Jennings E. Mortality and morbidity trends after the first year in survivors of acute myocardial infarction: a systematic review. BMC Cardiovascular Disorders. 2017 Feb 7;17(1):53. DOI: 10.1186/s12872-017-0482-9.Johansson S., Rosengren A., Young K., Jennings E. Mortality and morbidity trends after the first year in survivors of acute myocardial infarction: a systematic review. BMC Cardiovascular Disorders. 2017 Feb 7;17(1):53. DOI: 10.1186/s12872-017-0482-9.Arnold S.V., Smolderen K.G., Kennedy K.F., Li Y., Shore S., Stolker J.M., et al. Risk factors for rehospitalization for acute coronary syndromes and unplanned revascularization following acute myocardial infarction. Journal of the American Heart Association. 2015 Feb 9;4(2):e001352. DOI: 10.1161/JAHA.114.001352.Arnold S.V., Smolderen K.G., Kennedy K.F., Li Y., Shore S., Stolker J.M., et al. Risk factors for rehospitalization for acute coronary syndromes and unplanned revascularization following acute myocardial infarction. Journal of the American Heart Association. 2015 Feb 9;4(2):e001352. DOI: 10.1161/JAHA.114.001352.Sreenivasan J., Abu-Haniyeh A., Hooda U., Khan M.S., Aronow W.S., Michos E.D., et al. Rate, causes, and predictors of 90-day readmissions and the association with index hospitalization coronary revascularization following non-ST elevation myocardial infarction in the United States. Catheterization and Cardiovascular Interventions. 2021 Jul 1;98(1):12-21. DOI: 10.1002/ccd.29119.Sreenivasan J., Abu-Haniyeh A., Hooda U., Khan M.S., Aronow W.S., Michos E.D., et al. Rate, causes, and predictors of 90-day readmissions and the association with index hospitalization coronary revascularization following non-ST elevation myocardial infarction in the United States. Catheterization and Cardiovascular Interventions. 2021 Jul 1;98(1):12-21. DOI: 10.1002/ccd.29119.Buch P., Rasmussen S., Gislason G.H., Rasmussen J.N., Køber L., Gadsbøll N., et al. Temporal decline in the prognostic impact of a recurrent acute myocardial infarction 1985 to 2002. Heart. 2007 Feb;93(2):210-5. DOI: 10.1136/hrt.2006.092213.Buch P., Rasmussen S., Gislason G.H., Rasmussen J.N., Køber L., Gadsbøll N., et al. Temporal decline in the prognostic impact of a recurrent acute myocardial infarction 1985 to 2002. Heart. 2007 Feb;93(2):210-5. DOI: 10.1136/hrt.2006.092213.Chaudhry S.I., Khan R.F., Chen J., Dharmarajan K., Dodson J.A., Masoudi F.A., et al. National trends in recurrent AMI hospitalizations 1 year after acute myocardial infarction in Medicare beneficiaries: 1999-2010. Journal of the American Heart Association. 2014 Sep 23;3(5):e001197. DOI: 10.1161/JAHA.114.001197.Chaudhry S.I., Khan R.F., Chen J., Dharmarajan K., Dodson J.A., Masoudi F.A., et al. National trends in recurrent AMI hospitalizations 1 year after acute myocardial infarction in Medicare beneficiaries: 1999-2010. Journal of the American Heart Association. 2014 Sep 23;3(5):e001197. DOI: 10.1161/JAHA.114.001197.Brown T.M., Deng L., Becker D.J., Bittner V., Levitan E.B., Rosenson R.S., et al. Trends in mortality and recurrent coronary heart disease events after an acute myocardial infarction among Medicare beneficiaries, 2001-2009. American Heart Journal. 2015 Aug;170(2):249-55. DOI: 10.1016/j.ahj.2015.04.027.Brown T.M., Deng L., Becker D.J., Bittner V., Levitan E.B., Rosenson R.S., et al. Trends in mortality and recurrent coronary heart disease events after an acute myocardial infarction among Medicare beneficiaries, 2001-2009. American Heart Journal. 2015 Aug;170(2):249-55. DOI: 10.1016/j.ahj.2015.04.027.Hanssen M., Cottin Y., Khalife K., Hammer L., Goldstein P., Puymirat E., et al. French Registry on Acute ST-elevation and non ST-elevation Myocardial Infarction 2010. FAST-MI 2010. Heart. 2012 May;98(9):699-705. DOI: 10.1136/heartjnl-2012-301700.Hanssen M., Cottin Y., Khalife K., Hammer L., Goldstein P., Puymirat E., et al. French Registry on Acute ST-elevation and non ST-elevation Myocardial Infarction 2010. FAST-MI 2010. Heart. 2012 May;98(9):699-705. DOI: 10.1136/heartjnl-2012-301700.Kim L.K., Yeo I., Cheung J.W., Swaminathan R.V., Wong S.C., Charitakis K., et al. Thirty-Day Readmission Rates, Timing, Causes, and Costs after ST-Segment-Elevation Myocardial Infarction in the United States: A National Readmission Database Analysis 2010-2014. Journal of the American Heart Association. 2018 Sep 18;7(18):e009863. DOI: 10.1161/JAHA.118.009863.Kim L.K., Yeo I., Cheung J.W., Swaminathan R.V., Wong S.C., Charitakis K., et al. Thirty-Day Readmission Rates, Timing, Causes, and Costs after ST-Segment-Elevation Myocardial Infarction in the United States: A National Readmission Database Analysis 2010-2014. Journal of the American Heart Association. 2018 Sep 18;7(18):e009863. DOI: 10.1161/JAHA.118.009863.Culler S.D., Kugelmass A.D., Cohen D.J., Reynolds M.R., Katz M.R., Brown P.P., et al. Understanding Readmissions in Medicare Beneficiaries During the 90-Day Follow-Up Period of an Acute Myocardial Infarction Admission. Journal of the American Heart Association. 2019 Nov 5;8(21):e013513. DOI: 10.1161/JAHA.119.013513.Culler S.D., Kugelmass A.D., Cohen D.J., Reynolds M.R., Katz M.R., Brown P.P., et al. Understanding Readmissions in Medicare Beneficiaries During the 90-Day Follow-Up Period of an Acute Myocardial Infarction Admission. Journal of the American Heart Association. 2019 Nov 5;8(21):e013513. DOI: 10.1161/JAHA.119.013513.Сердечная А.Ю., Сукманова И.А. Клинико-гемодинамические характеристики и 3-летняя частота повторных сердечно-сосудистых событий у пациентов с инфарктом миокарда с подъемом сегмента ST и фармакоинвазивной стратегией. Бюллетень медицинской науки. 2024;2(34):64-74.Serdechnaya A.Yu., Sukmanova I.A. Clinical-hemodynamic characteristics and 3-year incidence of recurrent cardiovascular events in patients with ST-segment elevation myocardial infarction and pharmacoinvasive strategy. Bulletin of Medical Science. 2024;2(34):64-74. (In Russ.). DOI: 10.31684/25418475-2024-2-64.De Luca L., Paolucci L., Nusca A., Putini R.L., Mangiacapra F., Natale E., et al. Current management and prognosis of patients with recurrent myocardial infarction. Reviews in Cardiovascular Medicine. 2021 Sep 24;22(3):731-740. DOI: 10.31083/j.rcm2203080.De Luca L., Paolucci L., Nusca A., Putini R.L., Mangiacapra F., Natale E., et al. Current management and prognosis of patients with recurrent myocardial infarction. Reviews in Cardiovascular Medicine. 2021 Sep 24;22(3):731-740. DOI: 10.31083/j.rcm2203080.Jimenez-Quevedo P., Brugaletta S., Cequier A., Iñiguez A., Serra A., Mainar V., et al. Long-term impact of diabetes in patients with ST-segment elevation myocardial infarction: Insights from the EXAMINATION randomized trial. Catheterization and Cardiovascular Interventions. 2019 Dec 1;94(7):917-925. DOI: 10.1002/ccd.28194.Jimenez-Quevedo P., Brugaletta S., Cequier A., Iñiguez A., Serra A., Mainar V., et al. Long-term impact of diabetes in patients with ST-segment elevation myocardial infarction: Insights from the EXAMINATION randomized trial. Catheterization and Cardiovascular Interventions. 2019 Dec 1;94(7):917-925. DOI: 10.1002/ccd.28194.Шукурова С.М., Кабирзода Р.Х., Раджабова Г.М., Рахматуллоев Х.Ф., Файзуллоев А.И. Выбор современной стратегии лечения острого коронарного синдрома с подъемом сегмента ST. Журнал Здравоохранения Таджикистана. 2022;(3):119–127.Shukurova S.M., Kabirzoda R.Kh., Radjabova G.M., Rakhmatulloev Kh.F., Faizulloev A.I. Selection of a modern strategy for the treatment of acute coronary syndrome with ST-segment elevation. Journal of Healthcare of Tajikistan. 2022;(3):119–127. (In Russ.). DOI: 10.52888/0514-2515-2022-354-3-119-127.Mehta S.R., Wood D.A., Storey R.F., Mehran R., Bainey K.R., Nguyen H., et al. Complete Revascularization with Multivessel PCI for Myocardial Infarction. New England Journal of Medicine. 2019 Oct 10;381(15):1411-1421. DOI: 10.1056/NEJMoa1907775.Mehta S.R., Wood D.A., Storey R.F., Mehran R., Bainey K.R., Nguyen H., et al. Complete Revascularization with Multivessel PCI for Myocardial Infarction. New England Journal of Medicine. 2019 Oct 10;381(15):1411-1421. DOI: 10.1056/NEJMoa1907775.Collet J.P., Thiele H., Barbato E., Barthélémy O., Bauersachs J., Bhatt D.L., et al.; ESC Scientific Document Group. 2020 ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation. European Heart Journal. 2021 Apr 7;42(14):1289-1367. DOI: 10.1093/eurheartj/ehaa575.Collet J.P., Thiele H., Barbato E., Barthélémy O., Bauersachs J., Bhatt D.L., et al.; ESC Scientific Document Group. 2020 ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation. European Heart Journal. 2021 Apr 7;42(14):1289-1367. DOI: 10.1093/eurheartj/ehaa575.Yudi M.B., Clark D.J., Farouque O., Andrianopoulos N., Ajani A.E., Brennan A., et al.; Melbourne Interventional Group. Trends and predictors of recurrent acute coronary syndrome hospitalizations and unplanned revascularization after index acute myocardial infarction treated with percutaneous coronary intervention. American Heart Journal. 2019 Jun;212:134-143. DOI: 10.1016/j.ahj.2019.02.013.Yudi M.B., Clark D.J., Farouque O., Andrianopoulos N., Ajani A.E., Brennan A., et al.; Melbourne Interventional Group. Trends and predictors of recurrent acute coronary syndrome hospitalizations and unplanned revascularization after index acute myocardial infarction treated with percutaneous coronary intervention. American Heart Journal. 2019 Jun;212:134-143. DOI: 10.1016/j.ahj.2019.02.013.Spitaleri G., Brugaletta S., Scalone G., Moscarella E., Ortega-Paz L., et al. Role of ST-Segment Resolution in Patients With ST-Segment Elevation Myocardial Infarction Treated With Primary Percutaneous Coronary Intervention (from the 5-Year Outcomes of the EXAMINATION [Evaluation of the Xience-V Stent in Acute Myocardial Infarction] Trial). American Journal of Cardiology. 2018 May 1;121(9):1039-1045. DOI: 10.1016/j.amjcard.2018.01.015.Spitaleri G., Brugaletta S., Scalone G., Moscarella E., Ortega-Paz L., et al. Role of ST-Segment Resolution in Patients With ST-Segment Elevation Myocardial Infarction Treated With Primary Percutaneous Coronary Intervention (from the 5-Year Outcomes of the EXAMINATION [Evaluation of the Xience-V Stent in Acute Myocardial Infarction] Trial). American Journal of Cardiology. 2018 May 1;121(9):1039-1045. DOI: 10.1016/j.amjcard.2018.01.015.Олейников В.Э., Аверьянова Е.В., Тонкоглаз А.А., Лукьянова М.В. Предикторы повторных сердечно-сосудистых событий у пациентов с однососудистым поражением коронарных артерий, перенесших инфаркт миокарда с подъемом сегмента ST. Рациональная Фармакотерапия в Кардиологии. 2023;19(4):331-340.Olynikov V.E., Averyanova E.V., Tonkoglaz A.A., Lukyanova M.V. Predictors of recurrent cardiovascular events in patients with a single-vessel coronary artery disease after ST-segment elevation myocardial infarction. Rational Pharmacotherapy in Cardiology. 2023;19(4):331-340. (In Russ.). DOI: 10.20996/1819-6446-2023-2896.Ahmad Y., Howard J.P., Arnold A., Prasad M., Seligman H., et al. Complete Revascularization by Percutaneous Coronary Intervention for Patients with ST-Segment–Elevation Myocardial Infarction and Multivessel Coronary Artery Disease: an Updated Meta-Analysis of Randomized Trials. Journal of the American Heart Association. 2020 Jun 16;9(12):e015263. DOI: 10.1161/JAHA.119.015263.Ahmad Y., Howard J.P., Arnold A., Prasad M., Seligman H., et al. Complete Revascularization by Percutaneous Coronary Intervention for Patients with ST-Segment–Elevation Myocardial Infarction and Multivessel Coronary Artery Disease: an Updated Meta-Analysis of Randomized Trials. Journal of the American Heart Association. 2020 Jun 16;9(12):e015263. DOI: 10.1161/JAHA.119.015263.Gupta A., Bajaj N.S., Arora P., Arora G., Qamar A., Bhatt D.L. FFR-guided multivessel stenting reduces urgent revascularization compared with infarct-related artery only stenting in ST-elevation myocardial infarction: A meta-analysis of randomized controlled trials. International Journal of Cardiology. 2018 Feb 1;252:63-67. DOI: 10.1016/j.ijcard.2017.07.041.Gupta A., Bajaj N.S., Arora P., Arora G., Qamar A., Bhatt D.L. FFR-guided multivessel stenting reduces urgent revascularization compared with infarct-related artery only stenting in ST-elevation myocardial infarction: A meta-analysis of randomized controlled trials. International Journal of Cardiology. 2018 Feb 1;252:63-67. DOI: 10.1016/j.ijcard.2017.07.041.Wang L.J., Han S., Zhang X.H., Jin Y.Z. Fractional flow reserve-guided complete revascularization versus culprit-only revascularization in acute ST-segment elevation myocardial infarction and multi-vessel disease patients: a meta-analysis and systematic review. BMC Cardiovascular Disorders. 2019 Mar 1;19(1):49. DOI: 10.1186/s12872-019-1022-6.Wang L.J., Han S., Zhang X.H., Jin Y.Z. Fractional flow reserve-guided complete revascularization versus culprit-only revascularization in acute ST-segment elevation myocardial infarction and multi-vessel disease patients: a meta-analysis and systematic review. BMC Cardiovascular Disorders. 2019 Mar 1;19(1):49. DOI: 10.1186/s12872-019-1022-6.Puymirat E., Cayla G., Simon T., Steg P.G., Montalescot G., Durand-Zaleski I., et al.; FLOWER- MI Study Investigators. Multivessel PCI Guided by FFR or Angiography for Myocardial Infarction. New England Journal of Medicine. 2021 Jul 22;385(4):297-308. DOI: 10.1056/NEJMoa2104650.Puymirat E., Cayla G., Simon T., Steg P.G., Montalescot G., Durand-Zaleski I., et al.; FLOWER- MI Study Investigators. Multivessel PCI Guided by FFR or Angiography for Myocardial Infarction. New England Journal of Medicine. 2021 Jul 22;385(4):297-308. DOI: 10.1056/NEJMoa2104650.Pavasini R., Biscaglia S., Barbato E., Tebaldi M., Dudek D., Escaned J., et al. Complete revascularization reduces cardiovascular death in patients with ST-segment elevation myocardial infarction and multivessel disease: systematic review and metaanalysis of randomized clinical trials. European Heart Journal. 2020 Nov 7;41(42):4103-4110. DOI: 10.1093/eurheartj/ehz896.Pavasini R., Biscaglia S., Barbato E., Tebaldi M., Dudek D., Escaned J., et al. Complete revascularization reduces cardiovascular death in patients with ST-segment elevation myocardial infarction and multivessel disease: systematic review and metaanalysis of randomized clinical trials. European Heart Journal. 2020 Nov 7;41(42):4103-4110. DOI: 10.1093/eurheartj/ehz896.Bainey K.R., Engstrøm T., Smits P.C., Gershlick A.H., James S.K., Storey R.F., et al. Complete vs Culprit-Lesion-Only Revascularization for ST-Segment Elevation Myocardial Infarction: A Systematic Review and Meta-analysis. JAMA Cardiology. 2020 Aug 1;5(8):881-888. DOI: 10.1001/jamacardio.2020.1251.Bainey K.R., Engstrøm T., Smits P.C., Gershlick A.H., James S.K., Storey R.F., et al. Complete vs Culprit-Lesion-Only Revascularization for ST-Segment Elevation Myocardial Infarction: A Systematic Review and Meta-analysis. JAMA Cardiology. 2020 Aug 1;5(8):881-888. DOI: 10.1001/jamacardio.2020.1251.

The authors declare that there are no conflicts of interest present.