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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">thealth</journal-id><journal-title-group><journal-title xml:lang="ru">Здравоохранение Таджикистана</journal-title><trans-title-group xml:lang="en"><trans-title>Health care of Tajikistan</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0514-2415</issn><publisher><publisher-name>Редакция журнала «Здравоохранение Таджикистана»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.52888/0514-2515-2026-370-3-107-115</article-id><article-id custom-type="elpub" pub-id-type="custom">thealth-773</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL ARTICLES</subject></subj-group></article-categories><title-group><article-title>Допплерометрическая характеристика кровотока в маточных артериях у женщин при аденомиозе</article-title><trans-title-group xml:lang="en"><trans-title>Doppler ultrasound assessment of uterine artery blood flow in women with adenomyosis</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3851-2736</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Хушвахтова</surname><given-names>Э. Х.</given-names></name><name name-style="western" xml:lang="en"><surname>Khushvakhtova</surname><given-names>E. Kh.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Хушвахтова Эргашой Хушвахтовна - доктор медицинских наук, доцент, ведущий научный сотрудник гинекологического отдела</p><p>Душанбе</p></bio><bio xml:lang="en"><p>Ergashoy Khushvakhtovna Khushvakhtova - Doctor of Medical Sciences, Associate Professor, Leading Researcher of the Gynecological Department</p><p>Dushanbe</p></bio><email xlink:type="simple">hushvaxtova@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0002-3855-5864</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Акилова</surname><given-names>Д. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Akilova</surname><given-names>D. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Акилова Дилфуза Музаффаровна - заочный аспирант</p><p>Душанбе</p></bio><bio xml:lang="en"><p>Dilfuza Muzaffarovna Akilova - Correspondence Postgraduate Student</p><p>Dushanbe</p></bio><email xlink:type="simple">akilova_dilfuza@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0004-7350-5488</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Нарзуллаева</surname><given-names>З. Р.</given-names></name><name name-style="western" xml:lang="en"><surname>Narzullaeva</surname><given-names>Z. R.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Нарзуллаева Заррина Рахматуллаевна - к.м.н., доцент, зав.отд. функциональной диагностики</p><p>Душанбе</p></bio><bio xml:lang="en"><p>Zarrina Rakhmatullaevna Narzullaeva - MD, PhD, Associate Professor, Head of the Functional Diagnosis Department</p><p>Dushanbe</p></bio><email xlink:type="simple">z.narzullaeva@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ГУ «Таджикский научно-исследовательский институт акушерства, гинекологии и перинатологии»</institution><country>Таджикистан</country></aff><aff xml:lang="en"><institution>SI Tajik Research Institute of Obstetrics, Gynecology, and Perinatology</institution><country>Tajikistan</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2026</year></pub-date><pub-date pub-type="epub"><day>08</day><month>10</month><year>2026</year></pub-date><volume>0</volume><issue>3</issue><fpage>107</fpage><lpage>115</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Хушвахтова Э.Х., Акилова Д.М., Нарзуллаева З.Р., 2026</copyright-statement><copyright-year>2026</copyright-year><copyright-holder xml:lang="ru">Хушвахтова Э.Х., Акилова Д.М., Нарзуллаева З.Р.</copyright-holder><copyright-holder xml:lang="en">Khushvakhtova E.K., Akilova D.M., Narzullaeva Z.R.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.zdrav.tj/jour/article/view/773">https://www.zdrav.tj/jour/article/view/773</self-uri><abstract><sec><title>Цель</title><p>Цель: оценить изменения гемодинамики в маточных артериях при аденомиозе I-II степени.</p></sec><sec><title>Материал и методы</title><p>Материал и методы: проведено проспективное когортное исследование 45 женщин репродуктивного возраста. Основную группу составили 31 пациенток с аденомиозом (18 случаев - I степень, 13 случаев - II степень). Контрольную группу составили 14 женщин без гинекологической патологии и соматических заболеваний. Всем пациенткам проводилась спектральная допплерометрия маточных артерий с расчетом пульсационного индекса (ПИ), индекса резистентности (ИР) и систоло-диастолического отношения (СДО). Статистический анализ выполнен с использованием U-критерия Манна-Уитни.</p></sec><sec><title>Результаты</title><p>Результаты: при I степени отмечается снижение сосудистого сопротивления (ИР 0,77±0,003 против 0,91±0,005 в контроле; p&lt;0,001), что, вероятно, отражает усиление локальной васкуляризации и снижение тонуса артериол. При II степени заболевания отмечен феномен «псевдонормализации» показателей (ПИ 2,97±0,003), который может быть косвенно связан с последующими структурными перестройками миометрия, включая возможное развитие фиброзных изменений и компрессию сосудистого русла.</p></sec><sec><title>Заключение</title><p>Заключение: гемодинамический профиль матки при аденомиозе не является статичным, а трансформируется от гиперваскуляризации на начальных этапах к повышению резистентности при прогрессировании процесса.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Objective</title><p>Objective: to investigate changes in uterine artery blood flow across stages I–II of adenomyosis.  </p></sec><sec><title>Material and methods</title><p>Material and methods: a prospective cohort study was conducted in 45 women of reproductive age. The main group consisted of 31 patients with adenomyosis (18 with stage I, 13 with stage II). The control group included 14 healthy women without gynecological or other medical condition. All participants underwent spectral Doppler examination of the uterine arteries with assessment of the pulsatility index (PI), resistance index (RI), and systolic-diastolic ratio. Statistical analysis was performed using the Mann-Whitney U test.  </p></sec><sec><title>Results</title><p>Results: the study demonstrated pronounced stage-dependent variability of uterine artery blood flow parameters in adenomyosis. In stage I adenomyosis, a significant decrease in vascular resistance compared to the control group was observed (RI 0.77±0.003 vs 0.91±0.005; p&lt;0.001), which may reflect enhanced local vascularization and reduced arteriolar tone. In stage II adenomyosis, a phenomenon of “pseudonormalization” of hemodynamic parameters was identified (PI 2.97±0.003), which could be indirectly related to subsequent structural remodeling of the myometrium, including possible fibrotic changes and vascular compression.</p></sec><sec><title>Conclusions</title><p>Conclusions: the hemodynamic profile of uterine arteries in adenomyosis is dynamic and changes with disease progression: from hypervascularization and decreased vascular resistance in early stages to a relative increase in vascular resistance.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>внутренний эндометриоз</kwd><kwd>аденомиоз</kwd><kwd>маточные артерии</kwd><kwd>допплерометрия</kwd><kwd>гемодинамика&#13;
малого таза</kwd><kwd>неоангиогенез</kwd><kwd>зона соединения (junction zone)</kwd></kwd-group><kwd-group xml:lang="en"><kwd>adenomyosis</kwd><kwd>internal endometriosis</kwd><kwd>uterine arteries</kwd><kwd>Doppler ultrasound</kwd><kwd>pelvic hemodynamics</kwd><kwd>neoangiogenesis</kwd><kwd>junction zone</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Адамян Л.В., Андреева Е.Н., Артымук Н.В. и др. Эндометриоз: диагностика, лечение и реабилитация. Клинические рекомендации. Проблемы репродукции. 2021;27(3):1-103.</mixed-citation><mixed-citation xml:lang="en">Adamyan LV, Andreeva EN, Artymuk NV, et al. Endometriosis: diagnosis, treatment and rehabilitation. Clinical guidelines. Russian Journal of Human Reproduction. 2021;27(3):1-103. 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