Features of gestational period and perinatal outcomes in women with insulin resistance
https://doi.org/10.52888/0514-2515-2022-353-2-22-27
Abstract
Aim. To study the course of pregnancy and perinatal outcomes in women with insulin resistance.
Material and methods. A retrospective and prospective study of 102 women and their newborns who were born in the State Institution “Research Institute of Obstetrics, Gynecology, and Perinatology” for the period 2017-2019 was conducted. All pregnant women were divided into 3 groups according to the level of insulin resistance index (NOMA index). Group I - 42 pregnant women with developmental risk factors for diabetes with an insulin resistance index above 2.84. Group II consisted of 30 subjects with a NOMA index below 2.21, and Group III (n = 30) consisted of healthy pregnant women with a physiological course of pregnancy and labor.
Results. Newborns born to women with a NOMA index above 2.84 (pathological insulin resistance) have a high incidence of perinatal complications: central nervous system defects, various degrees of asphyxia, hypotrophy, and immaturity.
Conclusion. Insulin resistance in general affects pregnancy and has a negative impact on the course of pregnancy, causing a high incidence of complications such as threatened miscarriage, preeclampsia, chronic placental insufficiency and affecting perinatal outcomes.
About the Authors
Z. K. Bаymatova
State Institution Research Institute of Obstetrics, Gynecology and Perinatology
Tajikistan
Tajikistan
Zarina Kahorchanovna Baymatova, Senior Researcher
Tel: +992935354535
Obstetric Department
Sh. N. Oripova
State Institution Research Institute of Obstetrics, Gynecology and Perinatology
Tajikistan
Tajikistan
L. N. Mulkamonova
State Institution Research Institute of Obstetrics, Gynecology and Perinatology
Tajikistan
Tajikistan
N. S. Talbova
State Institution Research Institute of Obstetrics, Gynecology and Perinatology
Tajikistan
Tajikistan
P. Z. Kurbanova
State Institution Research Institute of Obstetrics, Gynecology and Perinatology
Tajikistan
Tajikistan
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Review
For citations:
Bаymatova Z.K., Oripova Sh.N., Mulkamonova L.N., Talbova N.S., Kurbanova P.Z. Features of gestational period and perinatal outcomes in women with insulin resistance. Health care of Tajikistan. 2022;(2):22-27. (In Russ.) https://doi.org/10.52888/0514-2515-2022-353-2-22-27
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