Features of hormonal function of the placenta in women with insulin resistance
https://doi.org/10.52888/0514-2515-2022-353-2-79-83
Abstract
Aim. To study the features of the hormonal function of the placenta in women with insulin resistance.
Material and methods. To study the hormonal function of the placenta of women with insulin resistance, 86 pregnant women in the third trimester of pregnancy were tested for the insulin resistance index (HOMA index), and the level of hormones in the blood. Group I of women (main) consisted of 30 pregnant women with risk factors for diabetes mellitus with an IRI above 2,84. Group II included 26 women of the same group, but with an IRI below 2,84. Group III (control) – 30 healthy women.
Results and discussion. With insulin resistance, the average level of hormones such as progesterone, placental lactogen, estradiol decreases, which indicates an unfavorable course of pregnancy and perinatal outcomes as a result of such a complication as placental insufficiency.
Conclusion. The study of the features of the development of placental insufficiency under the influence of various risk factors will allow for timely prevention and treatment of this pathology, which will improve perinatal outcomes in women with insulin resistance. IR contributes to the metabolic needs of the fetus and is the result of circulating placental hormones.
About the Author
Sh. N. Oripova
State Institution Tajik Research Institute of Obstetrics, Gynecology and Perinatology
Tajikistan
Tajikistan
Shabnam Nurulloevna Oripova, full-time postgraduate student
tel.: +992934333002
obstetrics department
References
1. Babaeva A. Kh. Dinamika platsentarnykh gormonov u beremennykh so srednetyazheloy i tyazheloy stepenyu preeklampsii [Dynamics of placental hormones in pregnant women with moderate and severe preeclampsia]. Aktualnye problemy meditsiny - Actual problems of medicine, 2018, Vol. 18, No. 3 (63), pp. 25-27.
2. Kamilova M. Ya. Meditsinskie i sotsialnye aspekty razvitiya platsentarnoy nedostatochnosti u beremennykh zhenshchin v sovremennykh usloviyakh Tadzhikistana [Medical and social aspects of the development of placental insufficiency in pregnant women in modern conditions of Tajikistan]. Dzurnal akusherstva i zhenskikh bolezney - Journal of obstetrics and women’s diseases, 2015, No. 6, pp. 26-30.
3. Oripova Sh. N. Ul’trazvukovaja diagnostika placentarnoy nedostatochnosti u zhenshin s insulinorezistentnost’yu [Ultrasound diagnostics of placental insufficiency of women with insulin resistance]. Vestnik poslediplomnogo obrazovaniya v sfere zdravoohraneniya – Herald of the institute of postgraduate education in health sphere, 2020, No. 1, pp. 69-74.
4. Pulodzoda F. P. Gormonalnaya funktsiya platsenty i oslozhneniya gestatsii u yunykh beremennykh [Hormonal function of the placenta and complications of gestation in young pregnant women]. Modar va kudak - Journal of Mother and Child, 2020, No. 4, pp. 46-48.
5. Rustamova M. S. Korrekciya insulinorezistentnosti u zhenshhin s giperplasticheskimi processami reproduktivnykh organov [Correction of insulin resistance in women with hyperplastic processes of reproductive organs]. Vestnik Akademii medicinskih nauk Tadzhikistana – Bulletin of the Academy of medical sciences of Tajikistan, 2017, No. 4 (24), pp. 62-65.
6. Trishkina A. G. Informativnost opredeleniya platsentarnogo laktogena i svobodnogo estriola dlya diagnostiki khronicheskoy platsentarnoy nedostatochnosti [Informativeness of the determination of placental lactogen and free estriol for the diagnosis of chronic placental insufficiency]. Akusherstvo i zhenskije bolezni - Journal of obstetrics and women’s diseases, 2011, Vol. 60, No. 2, pp. 63-64.
Review
For citations:
Oripova Sh.N. Features of hormonal function of the placenta in women with insulin resistance. Health care of Tajikistan. 2022;(2):78-82. (In Russ.) https://doi.org/10.52888/0514-2515-2022-353-2-79-83
Views:
306
Email this article 