The impact of medicinal treatment on quality of life in inflammatory bowel diseases: experience with the IBDQ questionnaire
https://doi.org/10.52888/0514-2515-2025-366-3-60-66
Abstract
Objective: To evaluate quality of life in patients with inflammatory bowel disease.
Materials and methods: A prospective cross-sectional study involving 46 patients was conducted with outpatient follow-up.
Results: Crohn’s disease was present in 32 (69.6%) of the total number of patients assessed (n = 46), and ulcerative colitis in 14 (30.4%). Of these patients, 25 (54.3%) were women and 21 (45.7%) were men. The mean patient age was 47.3 years. Non-smokers comprised 95.7% of participants. A history of surgery for the primary disease was noted in 11 patients (23.9%). Twenty (43.5%) patients received combination therapy, 21 (45.7%) received monotherapy, and the remaining five (10.9%) did not receive medical treatment. Significant improvement in quality of life was observed among patients treated with metipred.
Conclusions: Patients who received Metipred had the highest quality of life scores. No other statistically significant correlations with quality of life were found.
About the Authors
J. T. Rakhmonov
Department of Internal Medicine N.3, SEI Avicenna Tajik State Medical University
Tajikistan
Competing Interests:
Tajikistan
Rakhmonov Jamoliddin Tuymurodovich - assistant
Dushanbe
Competing Interests:
authors declare no conflict of interest
R. D. Dzhamolova
Department of Internal Medicine N.3, SEI Avicenna Tajik State Medical University
Tajikistan
Competing Interests:
Tajikistan
Dzhamolova Rukhshona Dzhalolidinovna - Candidate of Medical Sciences, Associate Professor
Dushanbe, Tel.: +992918724088
Competing Interests:
authors declare no conflict of interest
U. R. Rasulov
Department of Internal Medicine N.3, SEI Avicenna Tajik State Medical University
Tajikistan
Competing Interests:
Tajikistan
Rasulov Usmon Rasulovich - Doctor of Medical Sciences, Professor
Dushanbe
Competing Interests:
authors declare no conflict of interest
S. G. Ali-Zade
Department of Internal Medicine N.3, SEI Avicenna Tajik State Medical University
Tajikistan
Competing Interests:
Tajikistan
Ali-Zade Sukhrob Gaffarovich -Candidate of Medical Sciences, Associate Professor
Dushanbe
Competing Interests:
authors declare no conflict of interest
References
1. Bandel V.E., Mikhailova E.I., Trofimova N.V. Quality of life and psychoemotional disorders as a criterion for the effectiveness of therapy in patients with ulcerative colitis. Hepatology and gastroenterology. 2022;6(1):77– 81.
2. Bandel V.E., Mikhailova E.I. Mental health and quality of life in patients with ulcerative colitis. Health and environmental issues. 2021;18(3):42–46.
3. Rogler G, Singh A, Kavanaugh A, Rubin DT. Extraintestinal Manifestations of Inflammatory Bowel Disease: Current Concepts, Treatment, and Implications for Disease Management. Gastroenterology. 2021;161(4):1118-1132.
4. Kim B, Chae J, Kim EH, Yang HI et al. Physical activity and quality of life of patients with inflammatory bowel disease. Medicine (Baltimore). 2021;100(27):e26290.
5. Zhang J, Liu C, An P, Chen M. et al. Psychology Club of Inflammatory Bowel Disease Group, Chinese Society of Gastroenterology, Chinese Medical Association; Chinese Association for Mental Hygiene. Psychological symptoms and quality of life in patients with inflammatory bowel disease in China: A multicenter study. United European Gastroenterol J. 2024;12(3):374-389.
6. Raman M, Rajagopalan V, Kaur S. et al. Physical Activity in Patients With Inflammatory Bowel Disease: A Narrative Review. Inflamm Bowel Dis. 2022;28(7):1100-1111.
7. Zhang Y, Zhang L, Gao X. et al. Impact of malnutrition and sarcopenia on quality of life in patients with inflammatory bowel disease: A multicentre study. J Cachexia Sarcopenia Muscle. 2023 Dec;14(6):2663- 2675.
8. Scheffers LE, Vos IK, Utens EMWJ. et al. Physical Training and Healthy Diet Improved Bowel Symptoms, Quality of Life, and Fatigue in Children With Inflammatory Bowel Disease. J Pediatr Gastroenterol Nutr. 2023;77(2):214-221.
9. Di Candido F. Quality of Life in Inflammatory Bowel Diseases (IBDs) Patients after Surgery. Rev Recent Clin Trials. 2022;17(4):227-239.
Review
For citations:
Rakhmonov J.T., Dzhamolova R.D., Rasulov U.R., Ali-Zade S.G. The impact of medicinal treatment on quality of life in inflammatory bowel diseases: experience with the IBDQ questionnaire. Health care of Tajikistan. 2025;(3):60-66. (In Russ.) https://doi.org/10.52888/0514-2515-2025-366-3-60-66
Views:
26
Email this article 