Preview

Health care of Tajikistan

Advanced search

Current issues of clinical and epidemiological challenges associated with botulinum in the city of Tursunzade, Republic of Tajikistan

https://doi.org/10.52888/0514-2515-2026-369-2-72-81

Abstract

Objective: To study and analyze clinical and epidemiological features of foodborne botulism cases in the city of Tursunzade, Republic of Tajikistan, between 2020 and 2023.

Material and Methods: A retrospective analysis of medical records of patients diagnosed with botulism and admitted to the Infectious Diseases Department of Tursunzade Central Hospital was conducted. The diagnosis of botulism in all cases was based on clinical and epidemiological data and confirmed by laboratory testing.

Results: A total of 14 patients were observed. Of these, 3 were hospitalized in 2020, 7 in 2021, 3 in 2022, and 1 in 2023. Most patients were women: 12 (85.7%), while 2 (14.3%) were men. No cases were recorded among children. Among the patients, 9 (64.3%) were rural residents and 5 (35.7%) were urban residents. In all cases, infection occurred through the consumption of home-canned foods.

Conclusion: Botulism is characterized by a polymorphic clinical manifestation, which requires increased vigilance on the part of ophthalmologists, neurologists, and internists. This can be achieved by incorporating foodborne botulism as a dedicated topic into mandatory continuing medical education courses for physicians of various specialties.

About the Authors

J. E. Rakhmonov
SEI Avicenna Tajik State Medical University, Department of Infectious Diseases
Tajikistan

Rakhmonov Jamshed Erkinovich, Head of the Department of Infectious Diseases, Candidate of Medical Sciences, Associate Professor

tel.: +992919643312

Dushanbe



N. M. Gulyamova
SEI Avicenna Tajik State Medical University, Department of Infectious Diseases
Tajikistan

Gulyamova Nazira Minhojevna, Candidate of Medical Sciences, Assistant of the Department of Infectious Diseases

Dushanbe



A. A. Boymurodov
SEI Avicenna Tajik State Medical University, Department of Infectious Diseases
Tajikistan

Boimurodov Abdugaffor Avliyakulovich, Candidate of Medical Sciences, Assistant of the Department of Infectious Diseases

Dushanbe



M. P. Ashurov
SI Central District Hospital of Tursunzade (Infectious Diseases Department)
Tajikistan

Ashurov Mahmud Pardaevich

Tursunzade  



U. A. Aslonov
SI Central District Hospital of Tursunzade (Infectious Diseases Department)
Tajikistan

Аslonov Usmon Aslonjvich

Tursunzade 



References

1. Andreeva A.A., Kutisheva I.A., Martynova G.P., Vlasova N.A., Kartel T.S., Alekseenko A.N., Konchakov M.P. A case of botulism in an infant. Children’s infections. 2020;19(2):64-66. https://doi.org/10.22627/2072-8107-2020-19-2-64-66.(In Russ.).

2. Eruslanov B.V., Svetoch E.A., Mitsevich I.P. Botulism: characteristics of the pathogen and laboratory methods for its diagnosis. Bacteriology. 2018; (3) 4: 47–59. https://doi.org/10.20953/2500-1027-2018-4-47-59. (In Russ.).

3. Nikolaeva I.I., Gilmullina F.S., Kazantsev A.Yu., Fatkullina B.Sh. A case of foodborne botulism type F. Epidemiology and infectious diseases. 2022;(27)6:360-367. https://doi.org/10.17816/EID120021. (In Russ.).

4. Kuvshinova T.D., Makarova I.V., Chernyavskaya O.A., Osipova A.V., Belikova E.A., Timonova M.S. Analysis of epidemiological and clinical manifestations of foodborne botulism in the Volgograd region. Pacific Medical Journal. 2024; 3: 44–48. https://doi.org/10.34215/1609-1175-2024-3-44-48. (In Russ.).

5. Nikiforov V.V. Botulism. St. Petersburg, RF: Eco vector; 2024. 528c. https://doi.org//10.17816/b.bot2023. (In Russ.).

6. Nikolaeva I.V., Shestakova I.V., Murtazina G.Kh. Modern strategies for the diagnosis and treatment of Clostridium difficile infection (literature review). Acta Biomedica Scientifica. 2018;(3)1:34–42. https://doi.org/10.29413/ABS.20183.1.5. (In Russ.).

7. Eruslanov B.V., Svetoch E.A., Mitsevich I.P., Fursova N.K., Dyatlov I.A. Botulism: characteristics of the pathogen and laboratory methods for its diagnosis. Bacteriology. 2018;(3)4:47-59. https://doi.org/10.20953/2500-1027-2018-4-47-59. (In Russ.).

8. Ibatullin R.A., Magzhanov R.V. A case of iatrogenic botulism during botulinum therapy in clinical practice. Therapeutic archive. 2018; (90) 11: 102–104. https://doi.org/10.26442/terarkh20189011102-104. (In Russ.).

9. Malov V.A., Maleev V.V., Pokrovsky V.I. Botulinum therapy and iatrogenic botulism: an infectious disease specialist’s view of the problem. Infectious diseases. 2019; (17) 4: 55–61. https://doi.org/10.20953/1729-9225-2019-4-55-61. (In Russ.).

10. Ogoshkova N.V., Lyubimtseva O.A., Kuzmenkina K.S. Foodborne botulism: a clinical case. Infectious diseases: news, opinions, training. 2024;(13)3:129–135. https://doi.org/10.33029/2305-3496-2024-13-3-129-135. (In Russ.).

11. Kharchenko G.A., Kimirilova O.G., Kimirilov A.A. Difficulties in the differential diagnosis of botulism. Attending physician. 2020; 1:47–51. https://doi.org/10.26295/OS.2019.70.74.010. (In Russ.).

12. Amar CFL, Grant KA, McLauchlin J. Review of foodborne botulism in the UK: 2006–2024. Foods. 2025;14(15):2584. https://doi.org/10.3390/foods14152584

13. Lonati D, Schicchi F, Crevani M, Buscaglia E, Scaravaggi G, Maida F, Cirronis V, Petrolini VM, Locatelli CA. Foodborne Botulism: Clinical Diagnosis and Medical Treatment. Toxins. 2020;12(8):509. https://doi.org/10.3390/toxins12080509

14. Costa AM, Silva JM, Belém F, Silva LP, Ascensão M, Evangelista C. Foodborne botulism: a case report. Porto Biomed J. 2021;6(1):115. https://doi.org/10.1097/j.pbj.0000000000000115

15. Goldberg В, Danino D, Levinsky Y, Levy I, Straussberg R, Dabaja-Younis H, Guri A, et al. Infant Botulism, Israel, 2007-2021. Emerg. Infect. Dis. 2023;29(1):235-241. https://doi.org/10.3201/eid2902.220991

16. Rao AK, Sobel J, Chatham-Stephens K, Luquez C. Clinical Guidelines for Diagnosis and Treatment of Botulism, 2021. MMWR Recomm Rep. 2021; 70(2):1–30. https://doi.org/10.15585/mmwr.rr7002a1

17. Luguer C, Edwards L, Griffin C, Sobel J. Foodborne botulism outbreaks in the United States, 2001-2017. Front Microbiol. 2021;12:713101 https://doi.org/10.3389/fmicb.2021.713101

18. Rosen H.E., Kimura A.C., Crandall J., Poe A., Nash J., Boetzer J., et al. Foodborne botulism outbreak associated with commercial nacho cheese sauce from a gas station market. Clin. Infect. Dis. 2020;70(8):1695-1700. https://doi.org/10.1093/cid/ciz479

19. Sharma A. Botulinum toxin: bio warfare agent and vaccine development. Clin. Res. Trials. 2021;7:1-8. https://doi.org/10.15761/CRT.1000348

20. Howes C, Hiatt K, Turlington K, Foster C, Holloway A, Graciano AL, Custer J, et al. Botulism in the Pediatric Intensive Care Units in the United States: Interrogating a National Database. J Pediatr Intensive Care. 2020;9(1):12–15. https://doi.org/10.1055/s-0039-1695045


Review

For citations:


Rakhmonov J.E., Gulyamova N.M., Boymurodov A.A., Ashurov M.P., Aslonov U.A. Current issues of clinical and epidemiological challenges associated with botulinum in the city of Tursunzade, Republic of Tajikistan. Health care of Tajikistan. 2026;(2):72-81. (In Russ.) https://doi.org/10.52888/0514-2515-2026-369-2-72-81

Views: 14

JATS XML


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 0514-2415 (Print)