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Obstetric and perinatal outcomes in women with premature rupture of membranes according to the timing of delivery

https://doi.org/10.52888/0514-2515-2026-369-2-102-108

Abstract

Objective: To evaluate the clinical, social, and medical history characteristics of women with premature rupture of membranes (PROM) according to the gestational age at delivery.

Material and Methods: A retrospective analysis of 125 delivery records of women with premature rupture of membranes was conducted. The patients were divided into two groups: women with PROM who delivered at term (61 women), and women with PROM who delivered prematurely (64 women). All women underwent a full clinical, laboratory, and obstetric examination, including taking a medical history, physical examination, measurement of body mass index (BMI), identification of non-obstetric comorbidities, and pregnancy complications. Statistical analysis included parametric and non-parametric methods.

Results: A statistically significant increase in the incidence of fetal growth restriction (FGR) and induced labor was noted in women with PROM who delivered prematurely compared to women with PROM who delivered at term. Perinatal outcomes of preterm delivery in women with PROM were characterized by a high frequency of neonatal asphyxia (31.3% vs. 4.9%, p <0.001). Perinatal mortality was recorded in 5 instances (7.8%) among newborns of mothers with PROM and preterm labor.

Conclusion: Preterm delivery in women with PROM should be considered a condition of high perinatal risk, requiring early prediction, stratification, monitoring, and optimization of pregnancy and labor management.

About the Authors

F. Kh. Khamidova
SI Tajik Research Institute of Obstetrics, Gynecology and Perinatology
Tajikistan

Khamidova Faridabonu Khurshedovna - is a postgraduate student

Dushanbe 



G. K. Davlatzoda
SI Tajik Research Institute of Obstetrics, Gynecology and Perinatology
Tajikistan

Davlatzoda Guljakhon Kobilchonovna - MD, PhD, Associate Professor, Director

Dushanbe 



F. R. Ishan-Khojaeva
SI Tajik Research Institute of Obstetrics, Gynecology and Perinatology
Tajikistan

Ishan-Khodzhaeva Farangis Rustamovna – Candidate of Medical Sciences, Senior Researcher, Obstetrics Department

Dushanbe 



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For citations:


Khamidova F.Kh., Davlatzoda G.K., Ishan-Khojaeva F.R. Obstetric and perinatal outcomes in women with premature rupture of membranes according to the timing of delivery. Health care of Tajikistan. 2026;(2):102-108. (In Russ.) https://doi.org/10.52888/0514-2515-2026-369-2-102-108

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ISSN 0514-2415 (Print)