State of plasma hemostasis in newborn infants
https://doi.org/10.52888/0514-2515-2021-349-2-48-53
Abstract
Aim. To study the features of the plasma hemostasis in newborns with congenital IUI.
Material and methods. The observation of 52 newborns with intrauterine infections was conducted. All the children were divided into two groups. The first group included 36 (69, 2%) patients with a severe IUI and the second - 16 (30,8) patients with a very slow course of the pathological process.
Results and discussion. The results of the study showed that IUI in children has a generalized form of the course, with symptoms of microcirculatory dysfunction of the internal organs and systems.
Conclusion. The study of the plasma component of hemostasis showed multidirectional changes in it in the form of activation of plasma clotting factors, at the same time there was an increase in the duration and time of blood clotting, indicating the development of consumption coagulopathy in this category of patients, whose severity depends on the course of fetal infections and tropism of the pathogen to the organs and tissues. Identified changes in the plasma component in children with intrauterine infections dictate the need for timely adequate corrective therapy.
About the Authors
P. Q. Zainudinova
Department of pediatric diseases № 2, Avicenna Tajik State Medical University
Tajikistan
Tajikistan
Zainudinova Parvina Qurbonshoevna assistant at the department of pediatric diseases № 2 Avicenna Tajik State Medical University
Dushanbe, Javonon str., tel.: +992 904 48 19 80
K. I. Ismoilov
Department of pediatric diseases № 2, Avicenna Tajik State Medical University
Tajikistan
Tajikistan
Dushanbe
Q. Sayohati
Department of pediatric diseases № 2, Avicenna Tajik State Medical University
Tajikistan
Tajikistan
Dushanbe
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Review
For citations:
Zainudinova P.Q., Ismoilov K.I., Sayohati Q. State of plasma hemostasis in newborn infants. Health care of Tajikistan. 2021;(2):48-53. (In Russ.) https://doi.org/10.52888/0514-2515-2021-349-2-48-53
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