FEATURES OF HEMOSTATIC SHIFTS IN PREMATURE CHILDREN WITH PNEUMONIA

Abstract

Aim. To study the features of a hemostatic shift in premature infants with pneumonia. Material and methods. 32 preterm infants aged 9 days to 1 month with severe and very severe pneumonia were observed in the study. The first group included 19 children with severe pneumonia and the manifestation of 1st stage respiratory failure; the second group included 13 children with very severe pneumonia with respiratory failure of 2nd and 3rd stages. Examined children along with general clinical examination underwent coagulatory and paracoagulatory examination of hemostasis. Results and discussion. The coagulogram revealed a noticeable shortening of the coagulation time according to Lee-White in patients of the first group and a significant elongation in children of the second group compared to the same indicators in the control group. The average values of the prothrombin index, the degree of thrombotest, and fibrinogen in patients of the first group were lower, while patients of the second group showed significantly lower indices than healthy patients and patients of the first group. Fibrinolytic activity in patients of the first group was within a normal range, while patients of the second group had significantly higher indices than a control group. Conclusion Thus, premature infants with severe pneumonia show moderate and premature patients with a very severe course of the pneumonic process show significant hemostatic shifts.