INDICATORS OF BLOOD TOXICITY IN VARIOUS VASCULAR BEDS IN PUERPERANTS WITH HEPATOPULMONARY SYNDROME WHO HAD SEVERE PREECLAMPSIA AND ECLAMPSY

Abstract

Purpose of the study. To study the peculiarities of blood toxicity in various vascular beds and the state of the lungs detoxification function in puerperants with hepatopulmonary syndrome who had severe preeclampsia and eclampsia.

Materials and methods. The study results of 54 women who had severe preeclampsia and eclampsia which was complicated by hepatopulmonary syndrome in the postpartum period and 20 generally healthy women were observed. Depending on the severity of condition all patients were divided into 3 groups. The first group consisted of 15 (27.8%) patients with an average severity of the condition. The second group included 22 (40,7%) patients with a severe condition and the third group had 17 (31,5%) patients with an extremely severe condition. All the subjects underwent screening of venous blood, mixed venous blood, and arterial blood.

Results. The study revealed that puerperants with the hepatopulmonary syndrome have detoxification mechanisms in their lungs that act against endogenous toxic substances and affect the entire spectrum of toxic substances.

Сonclusion. The functional state of the detoxification function of lungs depends on the severity of the hepatopulmonary syndrome course, as well as the functioning of other detoxifying systems and excretory organs. It also has stages of disorder (compensated, sub compensated and decompensated) that can be used in early diagnosis of the endogenous intoxication syndrome, the severity of the hepatopulmonary syndrome, development of the multiple organ failure syndrome and prognosis of outcomes.