ON THE ISSUE OF COMBINED ANTI-RELAPSE TREATMENT OF LARYNGEAL PAPILLOMATOSIS IN CHILDREN
Abstract
Aim. To improve the methods of combined anti-relapse treatment of laryngeal papillomatosis in children.
Materials and methods. A comparative analysis of the results treatment of 42 patients with laryngeal papillomatosis with the use of combined anti-relapse treatment with Laferobion, Immunomax, and bio supplements containing calcium and zinc and a traditional therapy was carried out.
Results. The clinical effectiveness of the treatment was evaluated by improved voice function and reduction of the relapse number. In patients of group-I, relapses were observed in 5% of patients after a year. Almost 50% of patients got back the normal state of T and B-cells and significantly improved local immunity. In patients of group-II, relapses were observed in 18.2% of cases, almost four times more. They had to be hospitalized again and get repeated courses of combined surgical and complex conservative treatment.
Conclusion. The proposed method of the combined anti-relapse treatment of laryngeal papillomatosis in children fulfills the deficiency of the immune state of the patient’s organism, prolongs the recurrence periods, and most importantly, is a pathogenetically justified method. It allows recommending its implementation in clinical practice.
About the Authors
S. S. Shaidoev
State Education Establishment “Institute of Postgraduate Education in Health Sphere of the Republic of Tajikistan”
Tajikistan
Tajikistan
Department of Otorhinolaryngology
R. R. Rahmatulloev
State Education Establishment “Avicenna Tajik State Medical University”
Tajikistan
Tajikistan
Sh. B. Polvonov
State Education Establishment “National State University”
Tajikistan
Tajikistan
P. R. Muhtorova
State Education Establishment “Institute of Postgraduate Education in Health Sphere of the Republic of Tajikistan”
Tajikistan
Tajikistan
Muhtarova Parvina Rahmatovna - Assistant of the Department of Otorhinolaryngology
A. M. Sharipov
State Education Establishment “Avicenna Tajik State Medical University”
Tajikistan
Tajikistan
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Review
For citations:
Shaidoev S.S., Rahmatulloev R.R., Polvonov Sh.B., Muhtorova P.R., Sharipov A.M. ON THE ISSUE OF COMBINED ANTI-RELAPSE TREATMENT OF LARYNGEAL PAPILLOMATOSIS IN CHILDREN. Health care of Tajikistan. 2020;(3):69-73. (In Russ.)
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