PROGNOSTIC METHODS FOR THE STUDY OF WOMEN WITH BENIGN OVARIAN NEOPLASMS

Abstract

Aim. To study prognostic methods of research for benign ovarian neoplasms in women and to identify the most significant prognostic criteria for diagnosis. Material and methods. The study included 177 women with benign ovarian formations under observation at the Consultative and Diagnostic Polyclinic of the Scientific and Research Institute of Hygiene and Epidemiology, as well as those hospitalized at the gynecological department of the Institute from 2014 to 2018. All patients underwent general clinical examination. The echographic study and doplerometry with “Aloka” production equipment were performed. Tumor markers CA-125, REA, CA 19-9 were studied according to standard methods. The immune-histochemical analysis was also performed. Results. A correlation between prognostic criteria of the benign ovarian tumor was made. There is a direct relation between the tumor blood flow resistance index and a tumor marker CA 125. The relationship between CA 125 and the malignancy index was also revealed. Conclusions: One of the essential criteria for eliminating the malignancy of ovarian formation is the calculation of the malignancy index. The analysis confirms the importance of MI as a criterion of malignancy in the preoperative diagnosis of patients with cystic ovarian formations. A differentiated approach according to malignancy index and vascular Dopplerometry allows optimizing the organizational aspects of managing such patients by changing approach and sending the patient to a specialized institution