Influence of laparoscopic surgery for endometroid ovarian cysts on anti-mullerian hormone

Abstract

Aim. To study the effect of laparoscopic surgery for endometroid ovarian cysts on the level of anti-mullerian hormone as an indicator of ovarian reserve.

Materials and methods. This prospective study included 25 women with endometrioid ovarian cysts who were admitted to a tertiary-level clinical hospital. All patients underwent laparoscopic cystectomy. Serum levels of anti-mullerian hormone were measured preoperatively and three months postoperatively to assess the impact on ovarian reserve.

Research results. Of the 25 women enrolled in the study, 17 (68.0%) had a unilateral endometrioid cyst, while the remaining 8 (32.0%) had bilateral cysts. The average size of the endometrioid ovarian cysts, measured by transvaginal ultrasound, was 117.71 ± 13.97 mm³. The most common concomitant genital and extragenital pathologies were pelvic adhesions, uterine fibroids, diffuse toxic goiter, and chronic pyelonephritis. The mean preoperative level of anti-mullerian hormone was 5.82 ng/ ml, which slightly decreased to 5.08 ng/ml three months post-surgery.

Conclusions. Laparoscopic cystectomy is a beneficial option for patients with endometrioid cysts larger than 4 cm. This study demonstrates that the procedure effectively and safely minimizes ovarian tissue loss and preserves ovarian reserve. The slight decrease in anti-mullerian hormone levels post-surgery and the sustained rate of pregnancy onset affirm the efficacy of laparoscopic interventions in these cases.