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Results of the use of alveolar defect bed auto-osteoplasty in patients with bulbous bleeding using platelet-rich plasma and dressing material coated with glandular oxide nanoparticles

https://doi.org/10.52888/0514-2515-2024-360-1-85-89

Abstract

Aim. To improve the outcome of alveolar socket bleeding treatments by simultaneous stimulation of reparative processes using plasma-rich platelets in combination with a dressing material coated with nanoparticles.

Material and methods. This study involved 150 patients experiencing minor socket bleedings post-extraction. To arrest the bleeding, a dressing material coated with iron oxide nanoparticles was applied in conjunction with platelet-rich plasma. To prepare the plasma, 45-60 ml of venous blood was drawn from each patient and subjected to a double centrifugation process. A membrane created from the platelet-rich fraction post-second centrifugation was used to cover the nanoparticlecoated dressing material.

Results. The combined application of these materials in the alveolar defect sites led to earlier detection of osseogenesis via X-ray examinations. This outcome is attributed to the enhanced osseoconductive properties conferred by the thrombocyte factors and the iron oxide nanoparticle-coated dressing material, facilitated by the fibrin network within the thrombocyterich plasma.

Conclusion. The use of autologous platelet-rich plasma in conjunction with nanoparticle-coated dressing materials has shown variability in the density of alveolar bone regeneration, with observed densities ranging from 650 to 800 Hounsfield units during extended follow-up periods.

About the Authors

R. I. Yulchiev
Department of Maxillofacial Surgery at the Avicenna Tajik State Medical University
Tajikistan

Yulchiev Rustam Ibrokhimovich – postgraduate student at the Department,

Dushanbe.



R. N. Dzhonibekova
Department of Maxillofacial Surgery at the Avicenna Tajik State Medical University
Tajikistan

Duahanbe.



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Review

For citations:


Yulchiev R.I., Dzhonibekova R.N. Results of the use of alveolar defect bed auto-osteoplasty in patients with bulbous bleeding using platelet-rich plasma and dressing material coated with glandular oxide nanoparticles. Health care of Tajikistan. 2024;(1):85-89. (In Russ.) https://doi.org/10.52888/0514-2515-2024-360-1-85-89

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ISSN 0514-2415 (Print)