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Herbal hepatoprotective mixture in the treatment of chronic lymphocytic leukemia

https://doi.org/10.52888/0514-2515-2025-367-4-28-34

Abstract

Objective: to evaluate the effectiveness of herbal hepatoprotective mixture as an adjunct treatment in patients with chronic lymphocytic leukemia.

Material and methods: the study was based on an analysis of 42 patients with confirmed diagnosis of chronic lymphocytic leukemia, who were treated in the hematology department of the National Medical Center “Shifobakhsh”. The herbal blend was used in patients whose clinical course was accompanied by hepatomegaly. The study group included 30 patients (71.4%), and the control group included 12 patients (28.5%). Patients in the study group received an herbal infusion of medicinal plants described by the authors as hepatoprotective: Silybum marianum, birch, mint, and immortelle. The control group did not receive the infusion.

Results: use of the herbal hepatoprotective infusion was associated with a positive effect, namely a reduction and normalization of liver size within a short period. In the main group, a liver size reduction of 1.5 cm was recorded in 7 patients (23.3%), 1.2 cm in 19 patients (63.3%), and 1.0 cm in 4 patients (13.3%). A slower decrease in liver size was observed in the control group, which did not receive the infusion (0.7 to 0.8 cm).

Conclusion: use of an herbal hepatoprotective mixture as an adjunct to standard therapy improves treatment outcomes and reduces the time to recovery of liver function in patients with chronic lymphocytic leukemia. 

About the Authors

G. Kh. Quvatzoda
SEI Avicenna Tajik State Medical University
Tajikistan

Quvatzoda Gulafzobonu Khairutdin, Postgraduate Student of the Department of Internal Diseases No. 3

Dushanbe



M. A. Shonazarova
SEI Avicenna Tajik State Medical University
Tajikistan

Shonazarova Mardzhona Ayniddinovna, Assistant of the Department of Internal Diseases No. 3

Dushanbe



K. Z. Urakov
SEI Avicenna Tajik State Medical University
Tajikistan

Urakov Komron Zokirovich, Candidate of Medical Sciences, Associate Professor, Head of the Department of Internal Diseases No. 3

Dushanbe



R. B. Rahimov
SI National Medical Center “Shifobakhsh”
Tajikistan

Rakhimov Begnazar Rakhmonovich, hematologist, Head of the Department of Adult Hematology

Dushanbe



N. T. Akhunova
SEI Institute of Postgraduate Education in Healthcare of the Republic of Tajikistan
Tajikistan

Akhunova Nasiba Takhirovna - Candidate of Medical Sciences, Associate Professor, Head of the Department of Therapy with a Course in Gerontology and Hematology

Dushanbe



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Review

For citations:


Quvatzoda G.Kh., Shonazarova M.A., Urakov K.Z., Rahimov R.B., Akhunova N.T. Herbal hepatoprotective mixture in the treatment of chronic lymphocytic leukemia. Health care of Tajikistan. 2025;(4):28-34. (In Russ.) https://doi.org/10.52888/0514-2515-2025-367-4-28-34

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ISSN 0514-2415 (Print)