CLINICAL PECULIARITIES OF THE COURSE AND MODERN TREATMENT METHODS OF CONGENITAL TOXOPLASMOSIS IN NEWBORNS

Abstract

Aim. To study clinical peculiarities of the course and modern treatment methods of congenital toxoplasmosis in newborns. Material and methods. The paper presents the results of an examination of 18 newborns with congenital toxoplasmosis. Along with general clinical examination methods, enzyme immunoassay analysis of mother and child was conducted. Results. High somatic pathology was found during the analysis of case histories of mothers: anemia in 12 cases - 66,67%; acute respiratory infection in 9 cases - 50%; kidney diseases in 7 cases - 38,89%; hynecologic pathologies like endometritis in 9 cases - 33,33% and colpittis in 5 cases 27,7%; complicated obstetrics history like perinatal loss in 11 cases - 61,1%, spontaneous misscarrige in 7 cases - 38,89% cases, risk of misscariege and hestoses in 5 cases -27,78%, intrauterine fetal hypoxia in 6 cases - 33,33% and polyhydramnios in 4 cases - 22,22%; complications during birth like labor weakness in 10 cases - 55,56%, stimulation during labour in 9 cases - 50% and long dry period in 5 cases - 27,78%. Conclusion. The results have shown that congenital toxoplasmosis in newborns has severe generalized septic process course with a lesion of all organs and systems that causes polyorganic insufficiency. The organs that were involved mostly are lungs, umbilical wound, intestines, brain and bone marrow. The efficiency of the treatment depended on the severity and form of the disease.