Prognostic factors for early intra-abdominal postoperative complications after laparoscopic cholecystectomy
https://doi.org/10.52888/0514-2515-2026-369-2-32-42
Abstract
Objective: To determine prognostic risk factors for early intra-abdominal postoperative complications after laparoscopic cholecystectomy.
Material and Methods: A retrospective case-control study was conducted based on the records of 9472 patients who underwent laparoscopic cholecystectomy for calculous cholecystitis between 2015-2025. The main group included 297 patients with early intra-abdominal complications, while 9175 patients without complications formed the comparison group. At the first stage, Pearson’s chi-square test and Fisher’s exact test were used; at the second stage, univariate and multivariate logistic regression models with odds ratios and 95% confidence intervals were built. Model discrimination was assessed using the ROC curve.
Results: Early intra-abdominal complications developed in 3.1% of patients. Bile leakage predominated among the complications (60.3%). At the univariate stage, risk factors included perivesical inflammatory infiltrate, perivesical abscess, Mirizzi syndrome, anomalous anatomy of Calot’s triangle elements, liver cirrhosis, insufficient surgeon experience (fewer than 40-50 laparoscopic cholecystectomies), failure to achieve the critical view of safety and failure to perform timely conversion. Multivariate analysis identified perivesical abscess, Mirizzi syndrome, anomalous anatomy of Calot’s triangle elements, liver cirrhosis, insufficient surgeon experience, failure to achieve the critical view of safety and failure to perform timely conversion as independent predictors. The area under the ROC curve was 0.872.
Conclusion: The development of early intra-abdominal complications after laparoscopic cholecystectomy is determined by a combination of severe local inflammatory changes, anatomical complexity of the intervention, and intraoperative surgical tactics.
About the Authors
I. Ch. Isoev
SEI Avicenna Tajik State Medical University
Tajikistan
Tajikistan
Isoev Imomnazar Chorievich – full-time postgraduate student of the Department of Topographic Anatomy and Operative Surgery named after Professor M.K. Karimov
tel.: +992884319292
Dushanbe
R. N. Khaltachev
SEI Avicenna Tajik State Medical University
Tajikistan
Tajikistan
Khaltachev Rustam Nazargeldievich – full-time postgraduate student of the Department of Topographic Anatomy and Operative Surgery named after Professor M.K. Karimov
Dushanbe
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Review
For citations:
Isoev I.Ch., Khaltachev R.N. Prognostic factors for early intra-abdominal postoperative complications after laparoscopic cholecystectomy. Health care of Tajikistan. 2026;(2):32-42. (In Russ.) https://doi.org/10.52888/0514-2515-2026-369-2-32-42
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