A CLINICAL CASE OF A PATIENT WITH IMPERFECT OSTEOGENESIS
Abstract
The clinical case of imperfect osteogenesis of the 22-month young patient is described. Clinical and xray examination demonstrates the presence of the system osteoporosis with pathologic traumas, physical and kinetic development delay and signs of hypoplasia of some muscle groups. Densitometry showed the decrease of mineral density of the bone tissue. Laboratory tests showed a deviation of Ca, parathormone, vitamin D and alkaline phosphate. For the first time in Tajikistan patient with imperfect osteogenesis of the third type received therapy with inhibitors of osteoclast resorption – pomidrone acid.
About the Authors
N. A. Inoyatov
Department of Endocrinology of Tajik State Medical University named after Abuali Ibni Sino
Tajikistan
Tajikistan
Dushanbe
N. F. Niyazova
Department of Endocrinology of Tajik State Medical University named after Abuali Ibni Sino
Tajikistan
Tajikistan
Dushanbe
Sh. T. Samiyeva
Department of Endocrinology of Tajik State Medical University named after Abuali Ibni Sino
Tajikistan
Tajikistan
Dushanbe
A. A. Musoyev
Department of Endocrinology of Tajik State Medical University named after Abuali Ibni Sino
Tajikistan
Tajikistan
Musoyev Ashraf Ahmatovich – clinical resident
734003, Dushanbe, Navoi str. 35, Apt. 125
tel.: +992939959959
References
1. Buklaev D. S., Kostik M. M., Arganovich O. E., Trofimova S. I. Sindrom Bruka. Opisanie sluchaya [Brook syndrome. Case description]. Ortopediya, travmatologiya i vosstanovitelnaya khirurgiya detskogo vozrasta - Orthopedics, traumatology and reconstructive surgery of childhood, 2015, Vol. 3, No. 3, pp. 44-47
2. Marycheva N. M., Zhuchenko N. A., Kostik M. M., Kotalevskaya Yu. Yu., Beme A.A., Zhurkova N.V., Asanov A. Yu. Sravnitelnyy analiz klinicheskikh proyavleniy semeynykh i sporadicheskikh sluchaev nesovershennogo osteogeneza I tipa [Comparative analysis of the clinical signs of family and sporadic cases of imperfect osteogenesis of I type]. Prakticheskaya meditsina – Practical medicine, 2015, No. 1(86), pp. 81-84
3. Umarova Z. K., Mamadzhanova G. S., Mukaramova D.A. Klinika, diagnostika i lechenie detey s nesovershennym osteogenezom [Clinical picture, diagnosis and treatment of children with imperfect osteogenesis]. Vestnik Avitseny – Herald of Avicena, 2012, No. 3, pp. 150-3153.
4. Andiran N., Alikasifoglu A., Gonc N., Ozon A., Kandemir N., Yordam N. Cyclic pamidronate therapy in children with osteogenesis imperfecta: results of treatment and follow-up after discontinuation. Journal of Pediatric Endocrinology and Metabolism, 2008, Jan; 21(1), pp. 63-72.
5. Ben Amor I.M., Glorieux F.H., Rauch F. Genotype-Phenotype Correlations in Autosomal Dominant Osteogenesis Imperfecta. Journal of Osteoporosis, 2011.
6. Biggin A., Zheng L., Briody J.N., Coorey C.P., Munns C.F. The Long-Term Effects of Switching from Active Intravenous Bisphosphonate Treatment to Low- Dose Maintenance Therapy in Children with Osteogenesis Imperfecta. Hormone Research in Paediatrics, 2015, No. 83, pp. 183-189
7. Glorieux F. H., Bishop N. J., Plotkin H., Chabot G., Lanoue G., Travers R. Cyclic administration of pamidronate in children with severe osteogenesis imperfect. New England Journal of Medicine, 1998, Vol. 339 (14), pp. 947-52.
8. Van Dijk F. S., Cobben J. M., Kariminejad A., Maugeri A., Nikkels P.G., van Rijn R.R., Pals G. Osteogenesis Imperfecta: A Review with Clinical Examples. Mol Syndromol. 2011.
Review
For citations:
Inoyatov N.A., Niyazova N.F., Samiyeva Sh.T., Musoyev A.A. A CLINICAL CASE OF A PATIENT WITH IMPERFECT OSTEOGENESIS. Health care of Tajikistan. 2018;(1):69-73. (In Russ.)
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